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5-amino-1mq 99%Freeze-dried powder In stock Minimum Order Hot Selling

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CAS No.:

42464-96-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

TianJin

Brand:

Pharma;Conutrix

Packaging:

10 vials/box

Price valid (until):

2026-06-21

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Anhui Ruibang Trading Co., Ltd

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

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Product Description
Seller Information
Inquiry History

Description

  Product Detail

Basic Parameter Information

Full Name: 5-Amino-1-methylquinolinium Iodide (5-Amino-1MQ)

Chemical Formula: C₁₀H₁₁IN₂

Molecular Weight: 286.11 g/mol

CAS Number: 211180-27-1

Appearance: Off-white to pale light brown crystalline solid powder, individually sealed in vials (main specifications: 10mg / 50mg / 100mg)

Purity: ≥99% verified by HPLC analysis, a full set of COA quality inspection documents will be provided with each batch

R&D Background: 5-Amino-1MQ is a synthetic heterocyclic small-molecule selective enzyme inhibitor belonging to the quinolinium chemical family, distinct from polypeptide substances. It precisely targets nicotinamide N-methyltransferase (NNMT), a key metabolic enzyme abundantly expressed in adipose tissue, liver cells and aging somatic cells. Excess NNMT activity disrupts intracellular nicotinamide recycling balance, lowers endogenous NAD+ storage and disturbs overall lipid and energy metabolism within tissues. This high-purity lab-grade raw material is developed for chemical biology research, metabolic disorder mechanism testing, aging-related cell assays and hepatic lipid deposition preclinical exploration, widely adopted in biochemistry, obesity pathology and cellular energy metabolism laboratory projects.

2. Core Mechanism of Action

5-Amino-1MQ occupies the substrate binding pocket of NNMT to hinder the catalytic transformation of nicotinamide into inactive 1-methylnicotinamide, rebalancing intracellular redox circulation, methyl donor supply and energy operation pathways:

Block the catalytic function of NNMT to avoid excessive consumption of nicotinamide, retain adequate nicotinamide precursors to support stable intracellular NAD+ recycling and maintain sufficient NAD+ reserves inside cells;

Preserve the storage of endogenous S-adenosylmethionine methyl donors, ensuring adequate methyl groups for regular epigenetic modification and phospholipid metabolism across various tissue types;

Raise intracellular NAD+ levels to activate regulatory signals of sirtuin protein family, enhance the operational efficiency of mitochondrial oxidative metabolism and elevate baseline cellular energy expenditure capacity;

Restrain the overexpression of lipid synthesis related genes in adipocytes and hepatocytes, slow down neutral lipid accumulation and inhibit abnormal expansion of adipose tissue under high-nutrient culture environments;

Reduce the buildup of oxidative metabolites caused by insufficient NAD+ redox support, alleviate long-term oxidative stress damage to cell membranes and intracellular organelles in aged cell models;

Adjust metabolic signal output of fat cells to improve tissue nutrient sensitivity, relieve unbalanced glucose and lipid turnover induced by sustained metabolic overload.

3. Core Research Efficacy (For Research Laboratory Use Only)

NAD+ Homeostasis & Mitochondrial Energy Research

Core experimental probe for exploring nicotinamide salvage circulation, sirtuin activation and mitochondrial functional maintenance; suitable for cell culture assays focusing on coenzyme balance and bioenergetic efficiency detection.

Adipose Tissue Lipid Metabolism & Obesity Mechanism Research

Suppress de novo lipid synthesis and activate fat breakdown signals in adipocytes, key experimental raw material for adipocyte cultivation and tissue models simulating diet-induced metabolic imbalance.

Hepatic Steatosis & Liver Metabolic Regulation Research

Reduce abnormal lipid accumulation within hepatocytes and ease liver metabolic pressure, applied to cell-level exploration of pathological mechanisms linked to non-alcoholic fatty liver lesions.

Cellular Senescence & Anti-Aging Pathway Research

Replenish depleted NAD+ pools in aging somatic cells to relieve metabolic decline accompanied by senescence, auxiliary testing material for experiments researching organ aging and recovery of degenerative cell functions.

Epigenetic Methyl Donor Balance Research

Stabilize intracellular SAM reserves to support research on methylation-mediated epigenetic regulation, compatible with multi-omics analysis for profiling metabolic gene expression patterns.

Supplied as sealed crystalline powder with HPLC-tested purity ≥99%, mainstream vial specifications include 10mg, 50mg and 100mg. Every batch is attached with complete COA, MSDS and HPLC chromatogram test records.

As a high-selectivity small-molecule NNMT inhibitor, 5-Amino-1MQ acts as an essential laboratory tool to study the internal connection between NNMT enzyme activity, NAD+ coenzyme circulation and whole-body lipid-energy balance. Its compact quinolinium molecular structure delivers stable cell permeability and consistent target binding performance in various in vitro cell culture and tissue research systems.

It serves as indispensable research material for cell cultivation and tissue model experiments covering biochemical enzymology, NAD+ redox metabolism, adipose lipid regulation, hepatic fat deposition and cellular senescence biology.

Note: For laboratory research use only, not approved for human oral consumption or clinical therapeutic treatment.

We maintain sufficient inventory, complete export certification documents, door-to-door double clearance logistics service with full real-time tracking of all shipments.

  About us

Anhui Ruibang Trading Co., Ltd. was established with a clear mission: to simplify international trade for businesses of all sizes. We act as a bridge between manufacturers and global buyers, offering professional sourcing, quality inspection, order coordination, and logistics management.

Our team brings years of experience in cross-border trade, supplier networks, and export documentation. We understand the challenges of international business — language barriers, quality control, shipping complexities — and we solve them with a client-first approach.
At Ruibang Trading, we don’t just move goods; we build relationships. Whether you are looking for a reliable supplier, need help consolidating shipments, or want to expand your product line, we provide tailored solutions to meet your goals.
Our Commitment: Integrity, efficiency, and transparency in every transaction.

  Why choose us

Our products are of reliable quality and sell well all over the world, with partners across many countries and regions. We have professional technical support and complete after-sales teams to promptly respond to all your inquiries and demands.

We always strictly control product quality, adhere to honest business principles, and prioritize quality and service. With stable product strength and thoughtful services, we sincerely welcome global customers to negotiate cooperation and achieve win-win development together.

We have been deeply engaged in the peptide industry for many years, serving as a source biotechnology factory integrating R&D, synthesis, production and sales.

We strictly follow production and quality control standards, with the whole process adopting aseptic production and independent lyophilization and packaging. Our products feature stable appearance, good solubility and high activity retention.

We support trial orders with small quantities, bulk orders and customized formulas, providing one-stop solutions for foreign trade supply and private customization needs.

Our Advantages

  Packaging Process:

Certificates
Basic Info

Product Name:
5-Amino-1-methylquinolinium chloride

Other Name:
5-amino-1-methylquinolin-1-ium iodide;5-Amino-1methylquinolinium iodide;5-Amino-1-methylquinolinium;NNMTi,inhibit,fusion,muSC,muscle stem cell,NNMT,Inhibitor,regenerative;NNMTi 5-amino-1MQ;1-methylquinolin-1-ium-5-amine iodide;5-Amino-1-methyl-1-quinolinium Iodide;5-amino-1MQ/5-amino-1mq

CAS No.:
42464-96-0

Molecular Formula:
C10H11N2.I

InChIKeys:
JPEZFBFIRRAFNR-UHFFFAOYSA-N

Molecular Weight:
286.11

Exact Mass:
285.997

EC Number:
464-196-0

Color/Form:
Brown to reddish brown

Categories:
Bulk Drug Intermediates

Characteristics

PSA:
29.9

XLogP3:
-1.1683

Melting Point:
213-214 °C

Critical Temperature & Pressure:
Store at -20°C
Seller Information

Business Type:
Trader

Main Products:
Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

Location:
Hefei, Provincia de Anhui

Year of Establishment:
2026

Inquiry History

53 Inquiries

Country	Product	Purchase Quantity	Date Posted
New Zealand	NNMTi/5-amino-1MQ CAS number 42464-96-0	2 KG	Mar 15, 2026
Netherlands	Powder or capsules 5-Amino-1-methylquinolinium chloride (5-Amino-1MQ) CAS 42464-96-0	10 G	Apr 13, 2026
United States	Nnmti 5-Amino-1-Methylquinolin-1-Ium Iodide 99% CAS 42464-96-0	1 KG	Oct 6, 2023
United States	5-amino-1MQ/NNMTi 98% Peptide Raw Powder 42464-96-0 Senwayer	500 KG	Oct 22, 2023
United States	Hhd Bodyybuilding Peptide 5-Amino-1mq CAS 42464-96-0 Fat Burning Weight Loss 5 Amino 1mq 99% White Powder HHD	1 MT	Sep 7, 2023
United States	Hhd Bodyybuilding Peptide 5-Amino-1mq CAS 42464-96-0 Fat Burning Weight Loss 5 Amino 1mq 99% White Powder HHD	8 KG	Aug 22, 2023
Slovenia	Hhd Bodyybuilding Peptide 5-Amino-1mq CAS 42464-96-0 Fat Burning Weight Loss 5 Amino 1mq 99% White Powder HHD	50 G	Aug 12, 2023
United States	5-Amino-1mq	10 MG	Jan 4, 2026
Russia	NNMTi	15.00 G	Aug 14, 2024
United Kingdom	5-amino-1mq chloride	3 KG	Mar 13, 2026
United States	5 amino 1 mmq	1 KG	Jul 11, 2026
United States	5-Amino-1mq	3 G	Jun 10, 2026
United States	99% peptide raw powder	1 G	May 8, 2026
United States	5-Amino-1-methylquinolinium Chloride 5 amino 1mq	110 G	Jun 6, 2026
United States	5-amino-1mq	1 KG	Jun 4, 2026
Canada	5 amino 1 mq chloride	200 G	Mar 31, 2026
United States	5-amino-1MQ (chloride)	100 G	Mar 13, 2026
Brazil	5 Amino 1mq	500 MG	Mar 2, 2026
Thailand	5amino	10 MG	Mar 1, 2026
Canada	5 amino 1mq	100 G	Feb 8, 2026

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5-amino-1mq 99%Freeze-dried powder In stock Minimum Order Hot Selling

Product Description

Seller Information

Inquiry History

Basic Parameter Information

2. Core Mechanism of Action

3. Core Research Efficacy (For Research Laboratory Use Only)

NAD+ Homeostasis & Mitochondrial Energy Research

Adipose Tissue Lipid Metabolism & Obesity Mechanism Research

Hepatic Steatosis & Liver Metabolic Regulation Research

Cellular Senescence & Anti-Aging Pathway Research

Epigenetic Methyl Donor Balance Research

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