Name :Lucy
Whatsapp/wechat:+852 52639712
Email:Lucy@gglp1.com

Semeglutide is a novel GLP-1 analogue. Compared with liraglutide, semaglutide has a longer fat chain and increased hydrophobicity, but semaglutide is modified with a short chain of PEG, and its hydrophilicity is greatly enhanced. After PEG modification, it can not only tightly bind albumin, mask the hydrolysis site of DPP-4 enzyme, but also reduce renal excretion, prolong the biological half-life, and achieve the effect of long circulation.

What is Semaglutide?
Semaglutide is the newest GLP-1R agonist and was approved by the FDA as a once-weekly  for the treatment of T2DM in late 2017. The peptide is chemically similar to liraglutide, with the inclusion of two structural modifications (Lau, Bloch, et al., 2015). The first is the replacement of Gly with the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib) at position 2. The second is the attachment of octadecanoic diacid to the side chain of Lys-26 through a short polyethylene glycol (PEG) spacer and a γ-glutamic acid linker. The amino acid substitution renders the peptide more resistant to DPP-4 compared to liraglutide, and the presence of the 18-carbon fatty acid moiety results in a high binding affinity for serum albumin, which translates to a half-life of approximately 7 days in humans.
Function
1. • Helps slow food leaving your stomach
• Helps prevent your liver from making too much sugar
• Helps the pancreas produce more insul when your blood sugar levels are high
• Can help control blood glucose
• Can reduce hyperglycemia, especially after meals
• Can reduce fasting insul and fasting glucose
• Can reduce hemoglobin A1c
• Can decrease appetite and caloric intake, while inhibiting weight gain
• Has been shown to lower triglyceride levels and oxidative stress from high LDL
• Has been shown to help induce weight loss in obese patients with higher dosing
• Helps decrease leptin and increase leptin sensitivity
• Can increase the conversion of white fat to brown fat
2. Facilitates Weight Loss
Combats Diabetes
Addresses Alzheimer's Disease

Peptide Storage Guidelines: General Tips

When storing peptides, remember to:
• Store peptide in a cold, dry, dark place
• Avoid repeated freezing and thawing of peptide
• Avoid overexposure to the air
• Avoid light exposure
• Avoid storing peptides in solution long term
• Aliquot peptide according to experimental requirements

Shanxi Xinghengyuan Technology and Trade Co., Ltd. adheres to the corporate spirit of "Customer First, Integrity-Based" and has established long-term stable partnerships with numerous enterprises worldwide. We uphold the business philosophy of "Survive by Quality, Develop by Innovation", abide by honest business principles, and strictly follow the quality policy of "Quality First, Customer Satisfaction, Innovation-Oriented, People-Centered", with continuous self-improvement.Supported by scientific management systems, advanced equipment and continuous technological innovation, we strive to meet diverse customer needs. With excellent industry reputation and high-quality, reliable products, our company has earned consistent trust and praise from customers at home and abroad.

1. Higher quality products (>=99% purity) for most of peptides and raws.
2. Domestic warehouses and stocks: USA, Canada, Europe and Australia.
3. Ship worldwide with safe and secure lines: 100% delivery guaranteed. No worry about Customs issues.
4. Special Service: Drop-shipping if need.
5. Cheapest prices in the market, unbeatable！
6. Double-clearance express, safer and more efficient.

Q1: How to confirm the Product Quality before placing orders?
A: All products are produced under standardized production procedures and strict quality control. Complete quality test reports and product specifications can be provided for your reference, so you can fully confirm the product quality before ordering.
Q2: Can you supply free samples?
A: We do not provide sample service at present. All goods will be delivered in strict accordance with official test standards and finished product specifications to ensure stable and qualified quality for every batch.
Q3: How do you treat quality complaints?A: Every batch of products is strictly inspected by QC and verified by QA before delivery. Unqualified products will never be arranged for shipment. If any quality issue is confirmed on our side, we will provide a free replacement or full refund in a timely manner.
Q4: What's your MOQ ?
A: For high-value raw materials, the MOQ starts from 1g to 10g. For regular bulk products, the MOQ is 100g or 1kg.
Q5: Is there a discount ?
A: Yes. We support preferential pricing for bulk orders. The larger your order quantity, the more favorable the price will be.
Q6: How to start orders or make payments ?
A: You can send us your purchase plan or simple order confirmation via email or trade chat. We will issue a formal Proforma Invoice with official bank information for you, and you can complete the payment as per the invoice details.