99% Purity Tirzepatide Peptide GLP-1 Receptor and GIP Receptor Dual Agonist CAS 2023788-19-2 for Research Use

99% Purity Tirzepatide Peptide GLP-1 Receptor and GIP Receptor Dual Agonist CAS 2023788-19-2 for Research Use

Tirzepatide is a synthetic 39-amino-acid linear peptide that functions as a dual agonist at the human glucagon-like peptide-1 receptor (GLP-1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR). It is a unimolecular dual incretin agonist with a C20 fatty diacid moiety attached via a glutamic acid spacer and two AEEA linkers, which enables strong albumin binding and extended half-life suitable for research dosing schedules.

Tirzepatide is a synthetic 39-amino-acid linear peptide that functions as a dual agonist at the human glucagon-like peptide-1 receptor (GLP-1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR). It is a unimolecular dual incretin agonist with a C20 fatty diacid moiety attached via a glutamic acid spacer and two AEEA (aminoethoxyethoxyacetic acid) linkers. This structural modification enables strong and reversible albumin binding (>99%), which significantly reduces renal clearance and extends the half-life, making it suitable for sustained research dosing schedules.

Tirzepatide is supplied as a white to off-white lyophilized powder with ≥99% purity (tested by HPLC). It is available in eight different dosages ranging from 5mg to 60mg per vial (5mg, 10mg, 15mg, 20mg, 30mg, 40mg, 50mg, and 60mg), with a standard pack size of 10 vials per box. Each vial is sealed with an aluminum-plastic flip-off cap and clearly labeled with product name, dosage, and batch number for easy identification and traceability. The lyophilized form ensures long-term stability and facilitates convenient reconstitution with appropriate solvents prior to use.

For laboratory research purposes only. Not for human or veterinary use. Not for diagnostic or therapeutic applications.

This product is strictly manufactured under GMP-like conditions, ensuring batch-to-batch consistency and reliability. Each batch undergoes rigorous quality control, including HPLC for purity analysis (≥99%), Mass Spectrometry for molecular weight confirmation (4813.45 g/mol), and visual appearance inspection for color and physical state. Water content is analyzed using Karl Fischer titration, and bacterial endotoxin levels are tested to ensure the product meets established specifications for research-grade materials. A Certificate of Analysis (COA) documenting all test results is provided with each batch, and third-party testing is available upon request for customers requiring additional verification.

Key Research Applications: GLP-1 receptor signaling pathway studies investigating downstream cAMP and gene expression responses; GIP receptor mechanism research focusing on glucose-dependent insulinotropic effects; dual incretin agonist co-activation studies exploring potential synergistic signaling; metabolic pathway research examining glucose regulation and energy homeostasis; receptor binding affinity and functional activity assays using cell-based or membrane-based models; in vitro and in vivo laboratory experiments utilizing appropriate animal or cell culture models; and peptide-based research compound development for drug discovery and mechanism-of-action studies.

Storage and Handling: Store lyophilized powder at -20°C, protected from light, and keep the vial tightly sealed to prevent moisture absorption. Under these conditions, the product remains stable for 24 months from the date of manufacture. Prior to opening, allow the vial to reach room temperature to avoid condensation inside the container. Once reconstituted with an appropriate sterile solvent (such as bacteriostatic water or sterile PBS), the solution should be refrigerated at 2-8°C and used within the recommended timeframe, typically 7-14 days depending on the reconstitution buffer. Avoid repeated freeze-thaw cycles after reconstitution, as this may compromise peptide integrity, leading to aggregation or degradation. For long-term storage of reconstituted solutions, aliquot into single-use volumes and freeze at -80°C, but avoid multiple freeze-thaw cycles.

Tirzepatide is a high-purity (≥99% by HPLC) dual incretin agonist peptide supplied as a lyophilized powder, ideal for laboratory research applications. With eight available dosages ranging from 5mg to 60mg per vial, it offers flexibility for various experimental setups. Each batch undergoes strict quality control, including HPLC and Mass Spectrometry analysis, ensuring batch-to-batch consistency and reliability. All dosages are in stock with a lead time of 3-5 business days after payment confirmation. Global shipping options include special line/express (40,under5kg, 14days)andUPS/FedEx(40,under5kg, 14days)andUPS/FedEx(70, 7-10 days), with free shipping available for orders over $1000. OEM services such as custom vial dosage, vial cap color, and peptide blends are available for bulk orders.

Research Applications (for laboratory use only)

• GLP-1 receptor mechanism and signaling pathway studies

• GIP receptor binding affinity and agonist activity assays

• Dual incretin receptor co-activation research

• Metabolic pathway and glucose regulation mechanism investigations

• In vitro and in vivo laboratory experiments

• Peptide-based research compound development

Packaging Structure (From Outer to Inner)
Level Description
Outer Packaging Standard cardboard box
Middle Packaging Product box (branded/plain) containing a plastic box inside
Inner Packaging Plastic box holding 10 glass vials with foam or partition protection
Vial Clear glass vial, aluminum-plastic flip-off seal, labeled with product name, dosage, and batch number

Each Plastic Box Contains:
10 vials of peptide （5mg/10mg/15mg/20mg/30mg/40mg/50mg/60mg per vial, based on your order)
Each vial is individually sealed with label
Foam or plastic partition to prevent vials from bumping into each other

Shipping Methods & Delivery Time
Shipping Method Cost Delivery TimeSpecial Line/ Express $40 (under 5kg) ~14 days
UK Special Line Same as above ~25 days (slightly delayed)
UPS / FedEx $70 7-10 daysShipping Policies

Policy Details
Free Shipping On orders over $1000
Remote Area Fee Some remote areas may incur an extra $35 (as determined by FedEx/UPS)
Lead Time 3-5 business days after payment confirmation

Frequently Asked Questions (FAQ)
Q1: Can I get a sample before placing an order?

Yes, samples are available upon request. Samples are not provided for free. You will need to pay for both the sample cost and the shipping fee. The sample fee will be deducted from your bulk order payment once you proceed with a formal order.

Q2: What payment methods do you accept?

We accept wire transfer (T/T), PayPal, and bank transfer. You may choose the most convenient method for you.

Q3: How and when can I receive my order after payment?

Small quantity orders: Shipped via international express (DHL, FedEx, UPS, etc.). Delivery time: 7-10 days after shipment.

Large quantity orders: Shipped by sea. Delivery time: 15-30 days depending on the destination port.

Special line: ~14 days delivery time (under 5kg, $40).

Q4: Can I use my own label or packaging?

Yes, OEM service is available for bulk orders. We can customize labels, vial dosage, vial cap color, and packaging according to your requirements. Please contact us for details.

Q5: What is your MOQ (Minimum Order Quantity)?

Retail MOQ: 1 kit/dosage/item

Customized packaging (e.g., custom vial size, cap color): 20-50 kits/dosage/item

Q6: Do you provide a Certificate of Analysis (COA) with each order?

Yes, each batch comes with a COA (HPLC purity test report). Third-party testing is also available upon request.

Q7: How should I store the peptide?

Store at -20°C, protected from light, and keep sealed. Once reconstituted, refrigerate at 2-8°C and use within the recommended timeframe.

Q8: What documents will be included with my shipment?

Commercial invoice, packing list, COA, and MSDS will be included with each shipment.