cagrilintide|Premium in stock

  Product Detail  

Core Product Specifications

• CAS Number: 1415456-99-3
• Molecular Weight: 4409.01 g/mol
• Form: Sterile lyophilized white powder (acetate salt)
• Purity: HPLC‑verified ≥99.0% (single impurity ≤1.0%)
• Standard Vial Sizes: 5 mg, 10 mg, 20 mg (bulk available)
• Storage: 2–8°C refrigerated; stable for 24 months unopened
• Solubility: Reconstitute with bacteriostatic water/saline for research use
• Half‑Life: ~7 days (supports once‑weekly subcutaneous dosing)
• Endotoxin: <0.1 EU/mg (pyrogen‑free)

Premium Quality & Manufacturing Standards

1. HPLC & Mass Spec Validation: Confirms ≥99.0% purity and structural integrity
2. Endotoxin & Sterility Testing: Ensures pyrogen‑free, bacteria‑free product
3. Heavy Metal Analysis: Undetectable lead, arsenic, mercury, cadmium
4. Third‑Party COA: Full Certificate of Analysis included with every order
5. Stability Testing: Validates long‑term shelf life under recommended storage

Mechanism of Action

• Amylin Receptor (AMY1/2/3) Activation: Slows gastric emptying, suppresses glucagon, and enhances satiety via brainstem nuclei (area postrema, NTS), reducing food intake.
• Calcitonin Receptor (CTR) Agonism: Adds energy expenditure modulation and bone metabolism benefits, differentiating it from pramlintide.
• Lipidation Engineering: Reversible albumin binding extends half‑life to enable once‑weekly dosing, eliminating pramlintide’s thrice‑daily injection burden.

Key Research Applications

1. Obesity & Weight Management

• Monotherapy delivers ~8.0% weight loss at 68 weeks; in combination with semaglutide (CagriSema), achieves 20.4% weight loss in Phase 3 trials—far exceeding semaglutide alone (12.1%).
• Targets visceral adiposity and curbs hedonic hunger, supporting sustainable weight reduction.

2. Type 2 Diabetes & Glycemic Control

• Improves insulin sensitivity, reduces postprandial glucose spikes, and lowers HbA1c.
• CagriSema reduces HbA1c by 2.2% and body weight by 15.7% in T2D patients, outperforming semaglutide monotherapy.

3. Metabolic Syndrome

• Addresses multiple risk factors: weight, glucose, insulin resistance, and lipid profiles.
• Investigated for non‑alcoholic fatty liver disease (NAFLD) and cardiometabolic protection.

In Stock & Logistics Advantage

• Immediate Fulfillment: Orders processed and shipped within 1–3 business days.
• Global Delivery: Express courier, air freight, and sea freight options worldwide.
• Custom Solutions: Bulk powder (gram‑to‑kilogram) and tailored vial sizes available.
• Full Documentation: COA, MSDS, and customs clearance paperwork provided.

Why Choose Our Cagrilintide Premium?

• Unrivaled Purity: ≥99.0% HPLC‑verified, exceeding industry benchmarks.
• Long‑Acting Convenience: Once‑weekly dosing for research flexibility.
• Dual Receptor Activity: Unique AMYR/CTR agonism for superior metabolic effects.
• Research‑Grade Exclusivity: For laboratory use only; not for human consumption.
• Reliable Supply: Continuous large‑scale inventory eliminates lead‑time delays.