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2-Hydroxydecanedioic acid

Name: 2-Hydroxydecanedioic acid
Brand: Cuicheng Bio
SKU: pr2606081175
Price: 1000 USD
Availability: InStock

Unit Price:

$1000-1200/G FOB

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CAS No.:

103963-71-9

Grade:

Industrial Grade

Content:

98%

Port:

guangzhou

Brand:

Cuicheng Bio

Packaging:

1mg

Price valid (until):

2026-07-08

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Cuicheng Biomedical Technology

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

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Description
2-Hydroxydecanedioic acid (also commonly known as 2-hydroxysebacic acid or α-hydroxysebasate) is a medium-chain, hydroxylated dicarboxylic acid. Its primary function in biological systems is to serve as a critical metabolic diagnostic biomarker for peroxisomal oxidation disorders and fat metabolism shifts. [1, 2, 3, 4, 5]

Core Biological and Clinical Functions

Diagnostic Biomarker for Peroxisomal Disorders: 2-Hydroxydecanedioic acid serves as a hallmark urinary biomarker used to detect inborn errors of metabolism. Elevated excretion of its (2R) enantiomer in human urine points directly to peroxisomal diseases like Zellweger syndrome and neonatal adrenoleukodystrophy. When peroxisomes fail to break down long-chain or branched fatty acids, omega-oxidation paths accelerate, generating excess hydroxylated dicarboxylic intermediates. [1, 2]

Indicator of Medium-Chain Triglyceride (MCT) Metabolism: Beyond genetic disorders, this compound is highly sensitive to alternative fat metabolism. It is prominently detected and quantified in the urine of premature infants fed MCT-dense diets. Its presence acts as a direct metabolic read-out showing how immature or overwhelmed hepatic systems bypass normal beta-oxidation pathways. [1]

Urinary Anti-Fatigue Biomarker: In systemic wellness and sports metabolomics, 2-hydroxydecanedioic acid—as a downstream oxidation product of sebacic acid—has been identified as a reliable anti-fatigue biomarker. Fluctuations in its levels correspond to cellular energy conservation shifts and changes in mitochondrial efficiency under prolonged physical stress. [1, 2]

Food Intake Biomarker: In nutritional metabolomics, trace amounts of this compound are naturally present in standard meat choices like poultry (chicken), pork, and waterfowl (duck). Consequently, it is utilized as an objective dietary biomarker in large-scale studies to confirm and track specific animal protein consumption. [1, 2]
Basic Info

Product Name:
2-Hydroxydecanedioic acid

Other Name:
Decanedioic acid,2-hydroxy-;2-Hydroxydecanedioic acid;α-Hydroxysebacic acid;2-Hydroxysebacic acid

CAS No.:
103963-71-9

Molecular Formula:
C10H18O5

InChIKeys:
InChIKey=LPIOYESQKJFWPQ-UHFFFAOYSA-N

Molecular Weight:
218.25 g/mol

Exact Mass:
218.25

Categories:
Bulk Drug Intermediates

Characteristics

PSA:
94.8 Å²

Melting Point:
118-121 °C @ Solvent: Ethyl acetate

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Seller Information

Business Type:
Manufactory

Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

Year of Establishment:
2019
Country Product Purchase Quantity Date Posted

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2-Hydroxydecanedioic acid

Product Description

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