Raw Powder Infigratinib CAS 872511-34-7 with High Purity

Infigratinib is an oral selective fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor with stable chemical properties and high target selectivity. It is a novel targeted anticancer drug, officially approved for clinical use, and widely applied in pharmaceutical production, tumor targeted therapy and related pharmacological research fields

Function

Competitively bind to the ATP binding site of FGFR, block FGFR1/2/3 kinase activity and downstream signaling pathways.
Inhibit proliferation and angiogenesis of tumor cells carrying FGFR2 fusion or gene rearrangement, and induce tumor cell apoptosis.
Show potent inhibitory activity against FGFR family kinases, with low inhibitory effect on other kinases and relatively low off-target toxicity.
Improve the survival status of patients with advanced malignant tumors driven by abnormal FGFR signals.
Applications

Core API for oral targeted anticancer capsules for treating unresectable locally advanced or metastatic cholangiocarcinoma.
Active raw material for formulations targeting FGFR-driven tumors such as urothelial carcinoma.
Reference standard and experimental reagent for research on FGFR inhibitors and tumor targeted drugs.

Xi’an Fulecare biotech has high-technique enterprises with 10 years history,dedicate to separation, purification of the natural active ingredients production and sales.

We also produce international frontier dietary supplements such as granulated powder,solid drinks,tea sachets, capsules and tablets etc.

We have high grade clean workshop,800 square meters of inspection center equipped with more than 10 sets of HPLC,GC,IR,MASS instruments,these provides a full range of quality assurance to our products

The company has a perfect quality assurance system.We implement strict quality control standards and have passed the certification for the ISO9001 Quality Management System. The Quality Management Department is equipped with many sets of high performance liquid chromatography (HPLC)instruments, ultraviolet spectrophotometers (UV), several spectropolarimeters, a gas chromatograph (GC), melting point apparatus, and other advanced testing and experimental equipment. We make a detailed division of labor for technology research, and for quality assurance and quality control, so that we can conduct effective and comprehensive quality control in the production process. This also allows us to make comprehensive detection analysis of final products, thus ensuring products quality.