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1,2-Difluorobenzene367-11-3C6H4F2

2 Inquiries

Unit Price:

$33-34/MT FOB

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CAS No.:

367-11-3

Grade:

Pharmaceutical Grade

Content:

99.5%

Port:

上海

Brand:

OORENT

Packaging:

Vial/Bottle/Bag/Carton

Price valid (until):

2026-07-16

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Product Detail

1,2-Difluorobenzene Basic information

Product Name:	1,2-Difluorobenzene
Synonyms:	Adjacent two fluorine benzene;O-DIFLUOROBENZENE;2-Difluorobenzene;1,2-Difluorobenzene,98+%;o-Difluorobenzene,99%;1,2-Difluorobenzene 98%;1，2-Dfluorobenzene;1,2-Bifluorobenzene ,98%
CAS:	367-11-3
MF:	C6H4F2
MW:	114.09
EINECS:	206-680-7
Product Categories:	Aromatic Hydrocarbons (substituted) & Derivatives;Fluorobenzene;Aryl;C6;Halogenated Hydrocarbons;Aryl Fluorinated Building Blocks;Building Blocks;Chemical Synthesis;Fluorinated Building Blocks;Halogenated Hydrocarbons;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks;Isoquinolines ,Quinaldines ,Quinolines ,Quinazolines ,Indolines;Fluorine series;alkyl Fluorine;K00001
Mol File:	367-11-3.mol

1,2-Difluorobenzene Chemical Properties

Melting point	−34 °C(lit.)
Boiling point	92 °C(lit.)
density	1.158 g/mL at 25 °C(lit.)
refractive index	n20/D 1.443(lit.)
Fp	36 °F
storage temp.	Flammables area
solubility	Chloroform, Methanol
form	Liquid
color	Clear colorless
Specific Gravity	1.158
Water Solubility	Not miscible or difficult to mix in water.
BRN	1905113
Henry's Law Constant	1.3×10^-3 mol/(m³Pa) at 25℃, Brockbank (2013)
Dielectric constant	14.26
Stability:	Stable. Incompatible with strong oxidizing agents. Highly flammable. Note low flash point.
InChI	1S/C6H4F2/c7-5-3-1-2-4-6(5)8/h1-4H
InChIKey	GOYDNIKZWGIXJT-UHFFFAOYSA-N
SMILES	Fc1ccccc1F
CAS DataBase Reference	367-11-3(CAS DataBase Reference)
NIST Chemistry Reference	Benzene, 1,2-difluoro-(367-11-3)
EPA Substance Registry System	Benzene, 1,2-difluoro- (367-11-3)

Safety Information

Hazard Codes	F,Xn
Risk Statements	11-20-2017/11/20
Safety Statements	7-16-29-33-7/9
RIDADR	UN 1993 3/PG 2
WGK Germany	3
RTECS	CZ5655000
Hazard Note	Flammable
HazardClass	3
PackingGroup	II
HS Code	29036990
Storage Class	3 - Flammable liquids
Hazard Classifications	Flam. Liq. 2

MSDS Information

Provider	Language
1,2-Difluorobenzene	English
SigmaAldrich	English
ACROS	English
ALFA	English

1,2-Difluorobenzene Usage And Synthesis

Chemical Properties	colourless liquid
Uses	1,2-Difluorobenzene is used in electrochemical analysis of transition metal complexes. 1,2-difluorobenzene is also a potent inhibitor of NMDA receptor.
Uses	1,2-Difluorobenzene(1,2-DFB) has been used to study the mechanism of dissociation of o-, m- and p-difluorobenzene ions by threshold photoelectron photoion coincidence spectroscopy. It has been used to study the room temperature adsorption of 1,2-DFB, 1,2-dichlorobenzene and 1,2-dibromobenzene on Si(100)2x1 by X-ray photoelectron spectroscopy and temperature programmed desorption. It is used as solvent in electrochemical studies on transition metal complexes. It is also applied as a solvent useful for electrochemical studies on transition metal complexes.
Definition	ChEBI: A difluorobenzene carrying fluoro groups at positions 1 and 2.
General Description	1,2-Difluorobenzene undergoes defluorination under very mild conditions by H₂ in the presence of NaOAc over rhodium pyridylphosphine and bipyridyl complexes tethered on a silica-supported palladium catalyst.

1,2-Difluorobenzene Preparation Products And Raw materials

Raw materials

Hydrochloric acid-->Fluoroboric acid

Preparation Products

2,3-Difluorophenylboronic acid-->Benzeneacetonitrile, 2-fluoro-alpha,alpha-dimethyl--->2-Chloro-1-(3,4-difluoro-phenyl)-ethanone-->2,3-Difluorobenzaldehyde-->2,3-Difluorophenol-->CHEMBRDG-BB 4003866-->(S)-2-(3,4-Difluorophenyl)oxirane-->1,2-difluoro-4,5-dinitrobenzene-->(1R,2R)-2-(3,4-difluorophenyl)cyclopropane carboxaMide-->4,7-Bis(5-broMothiophen-2-yl)-5,6-difluorobenzo[c][1,2,5] thiadiazole-->(1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol-->(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid-->2-Bromo-4,5-difluorobenzonitrile-->3,4-Difluorobenzyl chloride-->METHYL 3,4-DIFLUOROBENZOATE-->1,4-DIBROMO-2,3-DIFLUOROBENZENE

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Basic Info

Product Name:

1,2-Difluorobenzene

Other Name:

Benzene,1,2-difluoro-;Benzene,o-difluoro-;1,2-Difluorobenzene;o-Difluorobenzene;NSC 10275

CAS No.:

367-11-3

Molecular Formula:

C6H4F2

InChIKeys:

InChIKey=GOYDNIKZWGIXJT-UHFFFAOYSA-N

Molecular Weight:

114.09

Exact Mass:

114.09

BRN:

1905113

EC Number:

206-680-7

UNII:

AW7QGMW29C

NSC Number:

10275

DSSTox ID:

DTXSID2075390

HScode:

29036990

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

XLogP3:

2.23

Appearance:

Clear colorless Liquid

Density:

1.1496 g/cm³ @ Temp: 25 °C

Melting Point:

-34 °C

Boiling Point:

94 °C

Flash Point:

36 °F

Refractive Index:

1.449

Water Solubility:

Not miscible or difficult to mix in water.

Storage Conditions:

Flammables area

Vapor Pressure:

53.39 mmHg

Toxicity:

Inhalation-Mouse LC50: 55 g/m3/2 hours

Flammability characteristics:

Flammable; heat decomposes toxic fluoride gas

See More 1,2-Difluorobenzene Properties 

Hazard Identification

Classification of the substance or mixture

Flammable liquids, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H225 Highly flammable liquid and vapour
Prevention	P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 Keep container tightly closed. P240 Ground and bond container and receiving equipment. P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment. P242 Use non-sparking tools. P243 Take action to prevent static discharges. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower]. P370+P378 In case of fire: Use ... to extinguish.
Storage	P403+P235 Store in a well-ventilated place. Keep cool.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 1,2-Difluorobenzene Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

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We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
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Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	1,2 Difluorobenzene	5 MT	Mar 25, 2026
India	1,2 Difluorobenzene	5 MT	Mar 24, 2026

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