 Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > 21-O-Tigloylgymnemagenin

21-O-Tigloylgymnemagenin

Unit Price:

$2000-2200/G EXW

Get Latest Price 

CAS No.:

1581276-63-2

Grade:

Industrial Grade

Content:

98%

Packaging:

5mg

Price valid (until):

2026-07-24

Contact Supplier

 Chat Now

Cuicheng Biomedical Technology

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

 Visit Store

Product Description
Seller Information

Description

21-O-Tigloylgymnemagenin is a bioactive triterpenoid compound naturally isolated from the leaves of the medicinal plant Gymnema sylvestre (commonly known as Gurmar). It primarily functions as a core intermediate building block for gymnemic acids, possessing anti-diabetic, anti-sweet, and antimicrobial properties.

When evaluating its biological functions, it acts through several specific mechanisms:

1. Invalidation of Sweet Taste Receptors

The molecule serves as a primary aglycone component of several gymnemic acids (such as Gymnemic Acid IV). When it interacts with the taste buds on the tongue, it temporarily binds to and blocks sweet taste receptors. This selectively numbs the ability to taste sweetness from natural sugars (sucrose) and artificial sweeteners alike.

2. Inhibition of Glucose Absorption

Glycosides containing the 21-O-tigloylgymnemagenin core structure function as potent inhibitors of Sodium-Dependent Glucose Transporter 1 (SGLT1). By blocking SGLT1 in the brush-border membranes of intestinal epithelial cells, the compound directly slows down and suppresses the absorption of glucose in the gastrointestinal tract, preventing spikes in post-meal blood sugar levels.

3. Antimicrobial Activity

Research indicates that 21-O-tigloylgymnemagenin possesses amphiphilic characteristics that can interact with microbial membranes. It has been shown to induce lipid flip-flop in cellular membranes, displaying notable antimicrobial potential that compromises the structural integrity of targeted pathogens.

4. Anti-Inflammatory Potential

Certain derivatives structurally linked to this compound (such as 28-acetyl-21-tigloylgymnemagenin) have shown substantial suppression of inflammation, performing comparably to standard nonsteroidal and steroidal anti-inflammatory medications in laboratory models.

Basic Info

Product Name:
(3beta,4alpha,16beta,21beta,22alpha)-Olean-12-ene-3,16,21,22,23,28-hexol 21-[(2E)-2-methyl-2-butenoate]

CAS No.:
1581276-63-2

Categories:
Bulk Drug Intermediates
Seller Information

Business Type:
Manufactory

Main Products:
Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5

Location:
Chuangzhi valley,Chuangzhi Industrial Park ,Hanzhong Economic and Technological Dvelopment Zone,Hanzhong City, Shaanxi Province

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
51-100

Year of Establishment:
2019
Country Product Purchase Quantity Date Posted

Post an enquiry for this product

More Choices

Product Name	Grade / Content	Price	Supplier Name	Details
(3beta,4alpha,16beta,21beta,22alpha)-Olean-12-ene-3,16,21,22,23,28-hexol 21-[(2E)-2-methyl-2-butenoate]	Industrial Grade/99		Shaanxi Dideu Medichem Co. Ltd	Inquiry

Hot Searches: r thioctic acid; formula for potassium hydroxide; 2-chlorobenzoic acid; methyl ethyl ketoxime; copper sulphide; what is the name of c9h16; chemiewerk; naclo compound; retatrutide price; international specialty products; caramel coloring; lead ii iodide



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.

21-O-Tigloylgymnemagenin

Product Description

Seller Information

More Choices