N-Methylquinoxalin-6-amine CAS 1338986-47-2 Purity 98% Pharmaceutical Intermediate for Antiviral & CNS Drug Synthesis

1. Product Overview

N-Methylquinoxalin-6-amine (CAS: 1338986-47-2) is a quinoxaline-based heterocyclic amine compound with the molecular formula C₉H₉N₃ and a molecular weight of 159.19 g/mol. It appears as a white to light yellow crystalline solid and is widely used as a key building block in pharmaceutical and fine chemical synthesis.

2. Key Features & Advantages

• High Purity: Available at ≥98% purity, suitable for demanding pharmaceutical applications.

• Versatile Intermediate: Features both a reactive amine group and a methyl-substituted quinoxaline core, enabling diverse derivatization pathways.

• Well-Characterized: Full analytical support including NMR, HPLC, and MS available upon request.

• Stable Supply: Consistently available in gram to kilogram scales to support R&D through to pilot production.

3. Main Applications

• Pharmaceutical Intermediate: Serves as a core scaffold in the synthesis of antiviral agents, including compounds targeting HIV.

• CNS Drug Discovery: Used in the development of heteroaryl compounds for treating central nervous system disorders such as schizophrenia, psychosis, and neurological conditions.

• Metabolic Disease Research: Incorporated into molecular frameworks for obesity and diabetes therapeutics.

• Custom Synthesis: Ideal for medicinal chemistry programs requiring quinoxaline-based building blocks.

4. Technical Specifications

5. Storage & Handling

• Storage: Store in a cool, dry place (recommended 2–8°C) in a tightly sealed container, protected from moisture and light.

• Handling: Use in a well-ventilated area. Avoid inhalation of dust or vapors. Wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat.

• Shelf Life: Stable for at least 2 years when stored under recommended conditions.

6. Safety Overview

N-Methylquinoxalin-6-amine is not classified as a hazardous substance under standard GHS criteria. However, as with all fine chemical intermediates, it should be handled with care:

• P101: If medical advice is needed, have the product container or label at hand.

• P102: Keep out of reach of children.

• P260: Do not breathe dust/fume/gas/mist/vapors/spray.

• P262: Do not get in eyes, on skin, or on clothing.

• P263: Avoid contact during pregnancy and breastfeeding.

A full Safety Data Sheet (SDS) is available upon request.

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