Propylarsonic Acid
1. Basic Identification
- IUPAC Name: Propylarsonic acid (1-propanearsonic acid)
- Synonyms: As-propylarsonic acid, Arsonic acid propyl ester, n-Propylarsonic acid
- EINECS No.: 203-484-7
- Molecular Formula: \(\boldsymbol{C_3H_9AsO_3}\)
- Molecular Weight: 168.02
- SMILES: CCCAs(O)=O
- UN Number: UN 3280
- HS Code: 2931900090
- Hazard Classification: Class 6.1 Toxic Substance, Packing Group II
- Chemical Category: Organoarsenic compound, industrial biocide, water treatment algaecide, wood preservative intermediate
2. Physical & Chemical Properties
Appearance
White crystalline solid powder, odorless; stable solid under normal temperature and pressure.
Physical Constants
| Parameter | Standard Value | Remarks |
| Melting Point | 134.5 ℃ | Melts completely without obvious decomposition at melting point |
| Boiling Point | ~354 ℃ (predicted, decomposes on strong heating) | Loses arsenic oxide under high-temperature pyrolysis |
| Solubility in Water | Freely soluble | Forms weakly acidic aqueous solution |
| Solubility in Organics | Soluble in methanol, ethanol; slightly soluble in acetone; insoluble in alkanes, benzene |
|
| pKa | 4.11 | Weak organic arsenic acid, can form soluble salts with alkalis |
| Density (solid) | ~1.72 g/cm³ |
|
| Stability | Stable in neutral & weakly acidic water; decomposes under strong alkaline heating to release toxic arsenic-containing fumes |
|
Core Chemical Characteristics
- Organoarsenic biocidal activity
The arsonic acid group inhibits enzyme metabolism of algae, bacteria and fungi; long-lasting biocidal effect, widely used in industrial circulating water anti-slime treatment. - Salt-forming property
Reacts with NaOH / KOH to produce soluble propylarsonate salts, which are more suitable for liquid biocide formulations. - Thermal decomposition risk
Intense heating generates highly toxic arsenic trioxide and propyl volatile substances; avoid high-temperature drying or incineration without special waste treatment. - Chelating performance
Weak chelation with heavy metal ions, reduces metal ion-induced microbial reproduction in water systems. - Incompatible materials: Strong alkalis, strong oxidants, reducing agents, acidic flocculants, edible raw materials.
3. Export Industrial Quality Specifications
Industrial Water Treatment Grade (≥98.0%)
| Test Item | Standard Spec | Test Method |
| Propylarsonic acid Assay | ≥98.0 % | Acid-base titration / HPLC |
| Moisture Content | ≤0.50 % | Karl Fischer Titration |
| Total Arsenic Impurity (inorganic As) | ≤50 ppm | ICP-MS |
| Heavy Metals (Pb, Cd, Hg) | ≤10 ppm | AAS |
| Insoluble Matter | ≤0.10 % | Gravimetric filtration |
| Color & Appearance | Uniform white crystalline powder, no yellow/brown discoloration | Visual Inspection |
Liquid Sodium Propylarsonate Formulation Grade
Neutralized aqueous solution, 40% active ingredient, low solid precipitation for cooling tower dosing.
4. Main Industrial Applications
4.1 Industrial Circulating Cooling Water Biocide (Largest Consumption)
- Broad-spectrum algaecide & slime controller for power plant, chemical factory, air-conditioning cooling towers; suppresses green algae, diatoms and heterotrophic bacteria to prevent pipeline blockage and microbial corrosion.
- Papermaking white water biocide, eliminates mold and slime microorganisms to improve paper surface smoothness and reduce paper breakage.
4.2 Wood & Leather Preservative Intermediate
- Raw material for low-toxicity organoarsenic wood anti-mildew agent, inhibits mold growth on plywood and solid wood.
- Tanning auxiliary fungicide to prevent raw hide mildew during storage and transportation.
4.3 Agricultural Auxiliary Biocide
Minor additive for crop irrigation water disinfection to control aquatic pathogenic fungi and nematodes in water.
4.4 Fine Chemical Laboratory Reagent
Standard organoarsenic reference material for environmental water arsenic residue detection and analysis calibration.
5. Toxicology, Health Hazards & First Aid
Toxicity Profile
- Acute Oral LD50 (Rat): 180–300 mg/kg (Category 3, toxic if swallowed)
- Dermal hazard: Moderate skin irritant; trace arsenic can be absorbed through damaged skin to cause chronic arsenic accumulation poisoning.
- Inhalation hazard: Dust irritates respiratory tract; long-term inhalation damages liver, kidney and peripheral nerves.
- Environmental hazard: Extremely toxic to fish, shrimp and all aquatic organisms; arsenic residues persistently contaminate soil and groundwater.
Exposure Symptoms
- Inhalation of crystal dust: Throat burning, persistent cough, headache, fatigue, numbness of limbs after long-term exposure.
- Skin contact: Erythema, itching, eczema-like allergic dermatitis; severe cases cause pigment deposition on skin.
- Eye splash: Severe conjunctival swelling, corneal irritation, blurred vision.
- Oral ingestion: Nausea, vomiting, abdominal colic, liver and kidney dysfunction, peripheral neuritis in chronic poisoning cases.
Complete First-Aid Procedures
- Inhalation: Transfer victim to fully ventilated fresh air; supply oxygen if breathing difficulty occurs, send to hospital for arsenic detoxification treatment.
- Skin Contact: Immediately remove all contaminated protective clothing; continuously rinse affected skin with large volume of running clean water for ≥20 minutes.
- Eye Contact: Force open eyelids, irrigate eyes with abundant sterile cold water non-stop for more than 15 minutes and consult an ophthalmologist urgently.
- Oral Intake: DO NOT induce vomiting; drink activated carbon suspension and rush to hospital for professional arsenic antidote therapy.
6. Storage, Handling & Incompatibility Rules
Mandatory Storage Conditions
- Warehouse classification: Special Class 6.1 toxic solid chemical warehouse, completely isolated from food, feed, drinking water additives and alkaline raw materials.
- Temperature control: Store at 10–28 ℃, avoid direct sunlight and high-temperature heat sources to prevent thermal decomposition.
- Sealing requirement: Hermetically sealed inner PE bag + outer 25kg paper drum packaging to prevent dust leakage and moisture absorption.
- Shelf life: 12 months under original intact sealed packaging; once opened, finish use within 45 days.
Strictly Separated Incompatible Materials
Strong sodium/potassium hydroxide, chlorine-based oxidants, sodium sulfide reducing agents, alum acidic flocculants, edible chemical raw materials.
Safe Operation Specifications
- Operators wear fully sealed dust-proof respirator, nitrile heavy-duty chemical-resistant gloves, impact safety goggles and dust-proof full-body protective overalls.
- All feeding, mixing and packaging processes must be equipped with local negative pressure exhaust ventilation to avoid dust floating in the workshop.
- Small leakage: Collect scattered white crystals with dry inert sand and transfer into sealed plastic hazardous waste drums marked arsenic toxic waste.
- Large leakage: Build sand retaining dikes to contain solid powder; strictly prevent rainwater washing into rivers, sewers or farmland soil.
7. Export Packaging & Global Transportation Regulations
Standard Export Packaging Modes
- Solid industrial bulk grade: 25kg composite paper drum with double inner PE liner bags
- Lab analytical reagent small package: 1kg / 5kg light-proof plastic bottle with outer carton protective packaging
UN Transport Compliance Rules
UN 3280, Class 6.1 Toxic Substance containing arsenic compounds, Packing Group II
- Road transport: Ventilated special toxic chemical vehicles, equipped with dust-proof cover and leakage collection trays, avoid long-distance high-temperature exposure.
- Ocean shipment: Comply with IMDG Code toxic goods regulations; affix Toxic Hazard & Marine Pollutant dual labels, stacking height ≤2 layers, segregated from food and oxidizer cargo holds.
- Loading ban: Mixed loading with alkaline chemicals, edible goods, feed and drinking water treatment additives is strictly prohibited.
Full Export Document Package
- Batch Certificate of Analysis (COA)
- GHS-compliant MSDS / SDS
- Technical Data Sheet (TDS)
- Marine Dangerous Goods Declaration
- Heavy Metal Arsenic Residue Test Report
- REACH Registration Compliance Document
8. GHS Global Hazard Label Statements
Signal Word: Danger
Hazard Statements:
H301 Toxic if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
H341 Suspected of causing genetic defects
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects
Precautionary Statements:
P261 Avoid breathing crystalline dust
P280 Wear dust mask, protective gloves and eye/face protection
P301+P310 IF SWALLOWED: Immediately call poison control center or doctor
P305+P351+P338 IF IN EYES: Rinse continuously with clean water for many minutes
P403+P235 Store in cool, dry, well ventilated warehouse, tightly sealed away from heat
P501 Dispose of all residues and empty packaging as arsenic-containing toxic hazardous waste per local environmental laws
9. Fire Emergency Disposal Plan
Approved Fire Extinguishing Agents
Dry chemical powder, carbon dioxide (CO₂), fine water mist
Forbidden Agents
Strong alkaline foam extinguishing agent (alkali triggers decomposition to release highly toxic arsenic oxide fumes)
Fire Site Operation Steps
- Fully evacuate all personnel to upwind safe zone, isolate hazard area ≥300 meters, cut all heat sources and ignition points.
- Continuously cool surrounding packaging drums with water mist to avoid thermal decomposition and toxic arsenic dust diffusion.
- Collect all fire residual solid waste and contaminated wastewater; deliver to professional hazardous waste incineration plant with arsenic recovery treatment, never discharge directly into water bodies or soil.
10. Printable Export COA Template
CERTIFICATE OF ANALYSIS
Product Name: Propylarsonic Acid
CAS No.: 107-34-6
Grade: Export Industrial Water Treatment Grade
Batch No.: ____________
Net Weight: 25kg/drum
Manufacture Date: ____________
| Test Item | Standard Spec | Test Result | Test Method |
| Propylarsonic Acid Purity | ≥98.0 % |
| Acid-Base Titration |
| Moisture Content | ≤0.50 % |
| Karl Fischer Titration |
| Inorganic Arsenic Impurity | ≤50 ppm |
| ICP-MS |
| Heavy Metals (Pb+Cd+Hg) | ≤10 ppm |
| AAS |
| Water Insoluble Substance | ≤0.10 % |
| Gravimetric Filtration |
| Appearance | Uniform white crystalline powder without discoloration | Visual Inspection |
|
Conclusion: This batch complies with export industrial standard of Propylarsonic Acid.
Inspector Signature: ____________
Issuance Date: ____________
11. E-commerce Listing Copy (For Chemical Platform Export)
Product Title
Propylarsonic Acid CAS 107-34-6 98% White Crystal Organoarsenic Biocide Industrial Circulating Cooling Water Algaecide Slime Controller Papermaking White Water Fungicide Wood Preservative Intermediate
Short Description
Propylarsonic acid (C₃H₉AsO₃, CAS 107-34-6) white toxic organoarsenic crystalline powder, broad-spectrum algaecide and anti-slime biocide. Mainly applied for power plant & factory cooling tower algae/bacteria inhibition, papermaking white water mildew control and wood anti-mildew raw material. Complete UN3280 Class 6.1 toxic dangerous goods export documents COA, MSDS and TDS available for global bulk drum shipment.
Full Description
Propylarsonic acid is a stable organoarsenic fine chemical supplied as white crystal solid with minimum 98% purity. Its unique arsonic acid functional group produces long-lasting inhibition effect on algae, slime-forming bacteria and mold, widely recognized as efficient industrial circulating water biocide with stable performance under neutral water quality environment.
Core downstream application sectors: cooling tower circulating water treatment biocide to eliminate green algae, diatoms and biofilm; papermaking process white water fungicide to reduce paper breakage and mold spots; plywood and solid wood anti-mildew preservative intermediate; irrigation water auxiliary disinfectant for crop planting; environmental testing lab arsenic standard reference reagent. We supply standard 98% solid industrial grade and customized neutralized liquid sodium propylarsonate formulation for automatic dosing systems.
Packed in double PE liner sealed 25kg paper drums for full-container sea shipment. Classified UN3280 Class 6.1 arsenic-containing toxic hazardous substance with marine pollutant risk, we provide complete IMDG transport, customs clearance and REACH compliance certificates for long-term stable global supply to water treatment factories and papermaking manufacturers.
