Retatrutide is a triple glucagon, GIP, and receptor agonist. Retatrutide showed glucose control and weight loss in patients with type 2 diabetes mellitus (T2DM).Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor .Retatrutide can be used for the research of obesity.Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C.
Function
1.Treatment of depression and anxiety disorders: Retatrutide has been shown to have antidepressant and anxiolytic effects in preclinical studies, suggesting that it could be a promising treatment option for individuals with these conditions.
2.Prevention of neurodegenerative diseases: Retatrutide has neuroprotective properties that may be useful in preventing or slowing the progression of neurodegenerative diseases such as Alzheimer's and Parkinson's.
3.Enhancement of cognitive function: Retatrutide has been shown to improve learning and memory in animal studies, suggesting that it could have potential as a cognitive enhancer in humans.
4.Treatment of chronic pain: Retatrutide has been shown to have analgesic effects in preclinical studies, suggesting that it could be a useful treatment option for individuals with chronic pain conditions.
5.Promotion of wound healing: Retatrutide has been shown to accelerate wound healing in animal studies, suggesting that it could have potential as a therapeutic agent for promoting wound healing in humans.
Application
1.Retatrutide is often used in the pharmaceutical industry, weight losing, etc.
2.Retatrutide is a kind of peptide product.
3.Retatrutide acetate can inhibited GCGR, GIPR and GLP-1R.
4.Retatrutide acetate is activated by glucagon receptors resulting in significant weight loss and increased energy expenditure.
5.Retatrutide acetate can be used in studies of obesity.
Mechanism of Action
It simultaneously activates three key metabolic receptors to comprehensively regulate blood sugar control, fat reduction and metabolism enhancement. - 1.GLP-1
- ·Suppresses appetite and delays gastric emptying to reduce calorie intake;
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- 2.GCGR
- ·Boosts hepatic fat oxidation and thermogenesis to elevate basal metabolic rate;
- ·Burns visceral fat and reduces hepatic lipid accumulation.
- 1.Weight Loss Outcomes
Dosage: of 4mg / 9mg / 12mg once weekly
Results after 80 weeks (non-diabetic obese patients):
- ·4mg group: Average weight loss of 19%
- ·9mg group: Average weight loss of 24%
- ·12mg group: Average weight loss of 28.3%
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- 2.Additional Benefits
- ·Blood glucose: Significantly reduces glycated hemoglobin (HbA1c) and improves insulin resistance.
- ·Blood lipids & blood pressure: Lowers triglycerides and LDL; systolic blood pressure decreases by 10-15 mmHg on average.
- ·Liver: Ameliorates hepatic steatosis, with potential application in treating metabolic dysfunction-associated steatotic liver disease (MASLD).
- ·Joints: Notably relieves pain and improves physical function in patients with knee osteoarthritis.
Our company was established in 2022. Our main products are various peptides， such as weight loss peptide, anti-wrinkle peptide, tanning titanium, and other products, reliable quality, committed to strict quality control and thoughtful customer service, our experienced staff is always available to discuss your requirements to ensure customer satisfaction.
We always put the value of our customers as our top priority, we focus on high quality, competitive price, flexible order quantity, timely delivery. Our products are mainly exported to European countries, the United Kingdom, the United States, Canada and Australia. Our products are widely recognized and trusted by users.
We have our own delivery line to Canada, USA, UK, Spain, Poland, Netherland, Germany, Russia, Kazakhstan, etc. Door to door without any customs clearance issues.
We therefore focus on sourcing materials of perfect quality and ensure strict internal process control.Our goal is to survive by quality and develop by reputation.
Our advantage: Safe, effective and efficient customer service. Our products are produced quickly and safely. Provide samples before regular order. We focus on serving foreign customers, our products sell well in many countries. We ensure quality products and reasonable prices. We have good after-sales service, solve any type of problem, the goal is to make every customer satisfied with our company and get the best reputation.
Constantly strive for high quality products, competitive prices, professional support, effective team, cooperative and honest cooperation, good after-sales work.
Q&A
Q: When can I receive the package?
A: It will be shipped as soon as possible after payment, and the shipping time is generally 7 to 15 days.
Q: What is the minimum amount I can order? A: The minimum quantity we can order is 1 box, which contains 10 vials. Q:How about the price? Can you make it cheaper?
A:We always take the customer's benefit as the top priority. Price is negotiable under different conditions, we are assuring you to get the most competitive price.
Q: How do i keep the peptides when i receive it ?
A: Peptides in the form of lyophilized powder can be transported at room temperature by vacuum packaging, while polypeptides in the dissolved state need to be refrigerated at 2°C - 8°C. For long-term storage, peptides should be stored in the form of lyophilized powder store at -20°C or -80°C in a sealed container with desiccant, which can avoid the degradation of peptides to the greatest extent.
Company Profile
HKX is a reliable manufacturer and exporter of peptide raw materials.
We have strong R&D capabilities and advanced production facilities. Our products cover various synthetic peptides and related raw materials, which are widely used in scientific research and pharmaceutical development. Every batch of goods undergoes rigorous laboratory testing to meet international quality standards.
We have years of international trade experience and a complete logistics system. Neutral packaging is used for all goods to comply with international shipping regulations. We provide flexible order solutions for customers, from small trial orders to large bulk purchases.
Sticking to the philosophy of Quality Priority and Customer Oriented, we sincerely welcome customers from all over the world to negotiate business and create win-win cooperation.
Why Choose Us
·Ultra-High Purity Each batch is synthesized and purified to >99% purity (HPLC), ensuring reliable and reproducible results in sensitive experiments.
·Accurate Dosing & Consistency Our peptides are precisely weighed and vacuum-sealed under sterile conditions. Batch-to-batch consistency is rigorously maintained.
·Endotoxin-Free & Sterile Processing Manufactured in a cleanroom environment, our peptides are free from endotoxins, microbial contamination, and other impurities that could interfere with cell-based or in vivo studies.
·Retail and bulk orders are accepted.
·Neutral packaging with full sealing for safe international shipping.
·Fast dispatch within 1-3 working days after payment confirmation.
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