Dulaglutide is a recombinant fusion long-chain GLP-1 analog polypeptide prepared by standardized peptide synthesis and multi-step chromatographic purification technology. It adopts a specific fusion fragment design to form a complete stable macromolecular spatial conformation with stable batch-to-batch component proportion.
This single-target fusion polypeptide serves as a core standardized experimental material widely applied in endocrinology, cell biology and molecular metabolic signal research fields. It is extensively adopted by university life science laboratories, biotechnology R&D centers and global academic research groups. Under strictly controlled sterile laboratory environments, researchers utilize Dulaglutide to carry out systematic basic research including fusion polypeptide structural characteristic identification, binding affinity analysis between polypeptide ligands and GLP-1 cell surface target receptors, intracellular multi-stage biochemical cascade reaction rules and downstream metabolic signal transmission network exploration.
Full-process closed-loop quality monitoring and batch full sampling inspection are implemented throughout the whole production line. Complete traceable test documents such as COA, HPLC chromatograms, SDS-PAGE electrophoresis and mass spectrum identity verification reports can be provided for each batch, ensuring stable molecular composition and highly repeatable experimental performance between different batches. This product is strictly limited to in vitro laboratory testing and academic research activities only.
High Purification Degree & Complete Macromolecular Structural Stability
Adopting multi-stage ion exchange and gel filtration chromatographic separation plus low-temperature sterile vacuum lyophilization processes, the overall purity reaches above 98%. HPLC, electrophoresis and mass spectrometry are adopted for full batch identity verification. Vacuum freeze-drying technology effectively locks intact fusion polypeptide spatial structure and avoids molecular denaturation or fragmentation, delivering accurate, stable and reproducible experimental data for long-cycle metabolic cell research projects.
Fast Dissolution & Simple Laboratory Operation
The fluffy loose lyophilized powder dissolves rapidly in all conventional lab aqueous solvents without extra solubilizing additives. Operators can conveniently prepare high-concentration stock solutions and working diluents, fully matching daily operation demands of cell incubation, GLP-1 receptor binding affinity detection and diversified in vitro biochemical analysis experiments.
Unique Fusion Fragment Research Value
With specific fusion chain structural design, this polypeptide presents distinct circulation and binding characteristics compared with short-chain unmodified GLP-1 analogs. It is the standardized experimental sample for studying fusion polypeptide molecular retention characteristics, long-acting ligand receptor binding kinetics and single-channel GLP-1 signal activation rules, supporting multiple professional research directions of incretin polypeptide mechanism research.
Comprehensive Traceable Quality Document System
Customers can apply for a full set of supporting certification materials on demand, including Certificate of Analysis, HPLC chromatogram records, SDS-PAGE test data, mass spectrum identification report and microbial limit inspection records. All production flows follow unified manufacturing specifications for biological laboratory peptide reagents, meeting quality access standards of research institutions in various regions worldwide.
Excellent Long-Term Low-Temperature Storage Stability
Equipped with light-blocking and moisture-proof fully sealed vial packaging, the product can maintain intact molecular conformation and stable biochemical properties for 24 months under -20°C storage environment. The prepared aqueous solution also keeps steady within the valid storage period, adapting to both short-term rapid detection tests and continuous long-cycle metabolic cell culture research.
Basic research on structural characteristics and physicochemical properties of fusion long-chain polypeptides
In vitro experimental analysis of binding interaction between fusion GLP-1 analogs and cell surface GLP-1 receptors
Exploration of intracellular single-channel signal cascade reactions triggered by fusion polypeptide ligands
Construction and optimization of in vitro pancreatic and adipocyte cell models for metabolic research
Comparative study on structure-activity relationship of short-chain GLP-1 and fusion long-chain GLP-1 analogs
Research on molecular transport and retention rules of fusion macromolecules in simulated biological microenvironment
Storage Requirements
All containers must be fully sealed to prevent moisture absorption and external microbial contamination. Store the product in dry, cool and dark low-temperature environment at -20°C. Keep away from direct sunlight, high temperature and damp air. Repeated freeze-thaw circulation of reconstituted liquid is strictly forbidden. It is recommended to divide dissolved solution into multiple small independent aliquots for single separate use. Store separately from strong oxidants and chemically incompatible lab reagents.
Standard Operating Specifications
Only professionally trained laboratory technicians are allowed to operate this product. Wear complete protective equipment including lab coat, anti-impact safety goggles and nitrile gloves during all operation steps. Complete powder dissolution and sample transfer work in sterile biosafety cabinet or clean bench to avoid particulate and bacterial contamination. Only qualified sterile purified water and standard PBS buffers can be used for dissolution preparation.
Waste Disposal Rules
Treat residual powder, waste liquid and empty packaging containers in strict accordance with local laboratory safety management codes and unified biological hazardous waste disposal standards. It is forbidden to pour any experimental waste into domestic garbage or public sewer pipelines.
Turkey
United States
