—— Product Specifications ——

—— Product Detail ——

Product Overview

Aprotinin is a serine protease inhibitor polypeptide with a molecular weight of approximately 6,511 Da. This white to off-white crystalline powder is a naturally occurring protein derived from bovine lung tissue, consisting of 58 amino acid residues. The compound inhibits various serine proteases including trypsin, chymotrypsin, plasmin, and kallikrein, making it valuable in biochemical research and pharmaceutical applications. It is widely used in protein purification to prevent proteolytic degradation, in cell culture media, and as a pharmaceutical agent in certain clinical procedures. Its inhibitory activity is based on the formation of stable enzyme-inhibitor complexes.

Synthetic Process

Aprotinin is obtained through the following routes:

• Extraction from bovine lung tissue: Aprotinin is extracted from bovine lung tissue using acid extraction and purified by chromatography.

• Purification: Multiple chromatographic steps (ion exchange, affinity, size exclusion) are employed to obtain high-purity material.

Mechanism of Action / Application Principles

• Protease Inhibition: Forms stable complexes with serine proteases, inhibiting their proteolytic activity.

• Protein Purification: Added to protein solutions to prevent proteolytic degradation during purification.

• Pharmaceutical Research: Used as a model inhibitor for studying protease-inhibitor interactions.

Quality Specifications

Each batch is accompanied by a Certificate of Analysis (COA).

Packaging & Storage

• Research quantities: 5mg, 25mg, 100mg amber glass vials

Storage conditions: Store in a tightly sealed container at -20°C or below, protected from light. Under recommended conditions, shelf life is 24 months.

— C ompany Profile ——

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

—— Q&A ——

Q1: How to confirm the product quality before placing orders?
A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

Q2: Can you supply free samples?
A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

Q3: How do you treat quality complaints?
A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

Q4: What is your MOQ? Is there a discount?
A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
Q: Is there a discount?
A: Yes, for larger quantities, we always support with better prices.

Q5: How to start orders or make payments?
A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.