Hexacosyl (E)-ferulate 98% Purity Natural Product Reference Standard High-Purity Research Compound CAS 63034-29-7 for Phytochemical Analysis and Pharm

Product Overview

Hexacosyl (E)-ferulate is a naturally occurring long-chain alkyl ester of ferulic acid, consisting of a ferulic acid moiety esterified with a hexacosyl (C26) fatty alcohol chain. Its molecular formula is C₃₆H₆₂O₄ with a molecular weight of approximately 558.9 g/mol. The compound features the characteristic (E)-configuration of the ferulic acid double bond, which contributes to its biological activity and stability.

This compound is predominantly isolated from plant sources, particularly from the roots and rhizomes of certain medicinal plants within the Apiaceae and Poaceae families, where it serves as a lipophilic storage form of ferulic acid. As a high-purity reference standard, it is widely employed in phytochemical analysis, quality control of botanical extracts, and pharmacological research.

Natural Sources and Biosynthesis

(E)-Ferulic acid hexacosyl ester is a naturally occurring constituent found in various plant species. It is biosynthesized through the esterification of ferulic acid, a key intermediate in the phenylpropanoid pathway, with hexacosanol (C26 primary alcohol). This esterification increases the lipophilicity of ferulic acid, facilitating its accumulation in lipid-rich plant tissues such as seed oils, cuticular waxes, and root exudates. The compound has been identified in species including Angelica sinensis, Ligusticum chuanxiong, and various cereal grains.

Biological Activities and Research Applications

Ferulic acid esters, including the hexacosyl derivative, have been associated with a range of biological activities attributed to the phenolic acid moiety:

Antioxidant Activity: The phenolic hydroxyl group of the ferulic acid portion exhibits free radical scavenging properties, contributing to cellular protection against oxidative stress

Anti-inflammatory Effects: Research indicates potential inhibition of pro-inflammatory mediators through modulation of NF-κB and MAPK signaling pathways

Skin Protection: As a lipophilic ferulic acid derivative, it demonstrates enhanced skin penetration and photoprotective properties

Cardiovascular Health: Preliminary studies suggest potential benefits in vascular function and lipid metabolism

This product is intended exclusively for research purposes, including in vitro assays, analytical method development, and pharmacological studies. It is not intended for human consumption or therapeutic use.

Quality Specifications

Our (E)-Hexacosyl ferulate is manufactured under strict quality control conditions:

Purity: ≥98.0% determined by HPLC area normalization

Identity confirmed by NMR spectroscopy and mass spectrometry

(E)-Configuration confirmed by NMR coupling constants

Free ferulic acid content: ≤1.0%

Each batch accompanied by comprehensive Certificate of Analysis (COA)

Stable for 36 months when stored at 2-8°C in sealed containers protected from light and moisture

Packaging & Shipping

We offer flexible packaging options to meet diverse research needs:

Research quantities: 20mg, 50mg, 100mg amber glass vials

Bulk quantities: custom packaging available upon request

Shipped at ambient temperature with desiccant

International shipping available with proper documentation

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.