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Tyra-300 CAS:2800223-30-5

Name: Tyra-300 CAS:2800223-30-5
Brand: Orient
SKU: pr2608241384
Price: 25 USD
Availability: InStock

TDS 214 Inquiries

Unit Price:

$25-30/MT FOB

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CAS No.:

2800223-30-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Qingdao

Brand:

Orient

Packaging:

25kg/bag,500kg/bag, customized

Sample Available:

Yes

Price valid (until):

2027-12-31

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Payment Terms:

100% TT in advance

Average Lead Time:

10 days

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Product Introduction

TYRA‑300, also known as Dabogratinib, CAS No.2800223‑30‑5, is a potent, reversible and orally‑active selective FGFR3 inhibitor. It shows high‑efficiency inhibitory activity against FGFR3 mutation and fusion, IC50 = 11 nM. Widely used for lab research, pharmacological study, anti‑tumor mechanism research of urothelial carcinoma and solid tumors.

Appearance: White to off‑white powder

Molecular Formula: C₂₅H₂₄Cl₂N₆O₃S

Molecular Weight: 559.47

Purity: ≥98% / ≥99% (HPLC)

Storage:‑20℃ sealed and protected from light

We are a professional fine chemical supplier with years of export experience to global markets. We maintain stable production capacity and strict quality control system for all materials. Complete test reports are available upon request.

Product Images

Factory Information

Production and R&D

Company Profile

We are a professional chemical foreign trade enterprise integrating R&D, production, customization and global sales, committed to providing high-quality chemical products and professional services worldwide. With years of experience in the chemical industry, we have built a complete industrial chain and won widespread recognition from customers with reliable quality, flexible customization and sincere service.

We are proud to own our own modern standard chemical factory, equipped with advanced automated production lines and strict quality control systems. Built in line with international standards and certified by relevant industries, our factory ensures standardized, safe and environment-friendly production. Every link from raw material input to product packaging is professionally operated and monitored, guaranteeing stable and high-quality products.

Understanding customers’ diverse needs, we have a professional customization team consisting of experienced chemical engineers. We provide one-stop customization solutions, including formula adjustment, specification customization and packaging design, to accurately meet both small-batch and large-scale customized needs, with close communication throughout the process.

Adhering to a global development strategy, our sales network covers over 100 countries and regions across Asia, Europe, Africa, the Americas and Oceania. We have established long-term cooperative relationships with distributors and end-users worldwide, winning their trust and favorable reviews with high-quality products, competitive prices and thoughtful after-sales service.

We adhere to the core values of "people-oriented, integrity-based". We care for our employees by providing a good working environment, competitive benefits and training channels, enabling them to grow with the enterprise. Upholding honest operation, we abide by international trade rules, fulfill contracts strictly and maintain a good reputation in the industry.

Looking ahead, we will continue to upgrade our R&D and production capabilities, expand the global sales network, and strive to become a world-class trusted chemical foreign trade enterprise. We sincerely welcome global customers to consult and cooperate with us for a better future.

Shipping Method

FAQ

Q1: How to place an order?

A: Please send us the product specifications and required quantity via email or online message. We will then confirm the order details with you.

Q2: How long will delivery take?

A: We use dedicated door‑to‑door shipping lines. After payment is confirmed, delivery normally takes 8‑15 working days.

Q3: Can I get a quantity discount?

A: Yes. We offer favorable discounted prices for bulk orders.

Q4: How should I store the products?

A: Please store in a cool and dry place. We recommend refrigerated storage at 2‑5°C.

ECHEMI Editorial Reference

Dabogratinib(TYRA-300) , a 3-pyridylindazole analog, is a reversible and selective inhibitor of FGFR3 with an IC50 of 11 nM in Ba/F3 cells. It also exhibit potent activity in human bladder cancer cell lines harboring FGFR3 activating fusions or mutations.

Certificates
- TDS
Basic Info

Product Name:
TYRA-300

Other Name:
TYRA-300;2,6-Diazaspiro[3.3]heptane, 2-[5-[5-[(1R)-1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]-2-pyridinyl]-6-(methylsulfonyl)-;(R)-5-(1-(3,5-Dichloropyridin-4-yl)ethoxy)-3-(6-(6-(methylsulfonyl)-2,6-diazaspiro[3.3]heptan-2-yl)pyridin-3-yl)-1H-indazole;TYRA-300(Dabogratinib);Tyra-300 99% Shaanxi Dideu Medichem

CAS No.:
2800223-30-5

Molecular Formula:
C25H24Cl2N6O3S

InChIKeys:
JOAFWIHZEBKYQK-OAHLLOKOSA-N

Molecular Weight:
559.47

EC Number:
610-261-8

Categories:
Bulk Drug Intermediates

Characteristics

Density:
1.58±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

Boiling Point:
791.2±70.0 °C(predicted)

PKA:
11.87±0.40(predicted)
Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10 days

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

214 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Tyra-300 CAS 2800223-30-5	9 G	Jul 8, 2026
United States	TYRA-300 CAS 2800223-30-5	8 G	Jul 14, 2026
Australia	Wholesale TYRA-300 Powder CAS 2800223-30-5 with Best Price	1 G	Sep 21, 2026
United States	Wholesale TYRA-300 Powder CAS 2800223-30-5 with Best Price	5 G	Sep 11, 2026
United States	High Quality TYRA-300 99% powder 2800223-30-5 Shaanxi Dideu Medichem Co.Ltd	8 G	Aug 2, 2026
Germany	TYRA-300	5 G	Aug 1, 2026
United States	TYRA-300	1 G	Oct 8, 2026
Spain	Dobagratinib	1 G	Oct 8, 2026
United States	Dabogratinib	2 G	Oct 8, 2026
United States	dabogratinib/ TYRA-300	1 G	Oct 7, 2026
United Kingdom	dabogratinib	100 G	Oct 7, 2026
United Arab Emirates	Tyra 300	10 MG	Oct 1, 2026
Austria	Dabogratinib	6 G	Sep 30, 2026
Germany	Dafogratinib	2 G	Sep 29, 2026
Germany	Dabogratinib	100 G	Sep 28, 2026
United States	Tyra-300	1 G	Sep 25, 2026
Austria	Dabogratinib	6 G	Sep 24, 2026
United States	dabogratinib	1 G	Sep 23, 2026
Thailand	Tyra-300	1 G	Sep 23, 2026
Egypt	TYRA_300	6 G	Sep 22, 2026

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Tyra-300 CAS:2800223-30-5

Product Description

Seller Information

Inquiry History

We are a professional fine chemical supplier with years of export experience to global markets. We maintain stable production capacity and strict quality control system for all materials. Complete test reports are available upon request.

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