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Progesterone 57-83-0 200-350-6

Name: Progesterone 57-83-0 200-350-6
Brand: OORENT
SKU: pr2610221925
Price: 33 USD
Availability: InStock

21 Inquiries

Unit Price:

$33-34/MT FOB

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CAS No.:

57-83-0

Grade:

Pharmaceutical Grade

Content:

99.5%

Port:

shanghai

Brand:

OORENT

Packaging:

Vial/Bottle/Bag/Carton

Sample Available:

Yes

Price valid (until):

2026-11-22

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Payment Terms:

100% TT in advance

Average Lead Time:

10 days

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Details
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Description

Product Detailv

3-Carbamyl-1-methylpyridinium chloride Basic information

Product Name:	3-Carbamyl-1-methylpyridinium chloride
Synonyms:	NICOTINAMIDE CHLOROMETHYLATE;N-METHYLNICOTINIC ACID AMIDE CHLORIDE SALT;N1-METHYLNICOTINAMIDE CHLORIDE;TRIGONELLAMIDE CHLORIDE;3-(aminocarbonyl)-1-methyl-pyridiniuchloride;3-carbamoyl-1-methyl-pyridiniuchloride;nicotinamidemethochloride;nicotinamidemethylchloride
CAS:	1005-24-9
MF:	C7H9ClN2O
MW:	172.61
EINECS:	463-670-7
Product Categories:	Pyridinium Compounds;API
Mol File:	1005-24-9.mol

3-Carbamyl-1-methylpyridinium chloride Chemical Properties

Melting point	207-209℃ (water acetone )
storage temp.	room temp
solubility	H2O: soluble15mg/mL, clear
form	crystalline
color	white
Water Solubility	almost transparency
Merck	14,9693
Cosmetics Ingredients Functions	SKIN CONDITIONING SKIN PROTECTING
InChI	1S/C7H8N2O.ClH/c1-9-4-2-3-6(5-9)7(8)10;/h2-5H,1H3,(H-,8,10);1H
InChIKey	BWVDQVQUNNBTLK-UHFFFAOYSA-N
SMILES	Cl.[n+]1(cc(ccc1)C(=N)[O-])C
CAS DataBase Reference	1005-24-9(CAS DataBase Reference)

Safety Information

WGK Germany	3
RTECS	UU1925000
HS Code	2933.39.9200
Storage Class	11 - Combustible Solids

MSDS Information

Provider	Language
SigmaAldrich	English

3-Carbamyl-1-methylpyridinium chloride Usage And Synthesis

Description	Nicotinamide is a precursor of NAD and NADP , which serve essential functions in modulating cellular redox status and controlling signaling and transcriptional events. 1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced by the action of nicotinamide N-methyltransferase (NNMT; ). It demonstrates antithrombotic and anti-inflammatory properties through direct action on the endothelium by a mechanism involving the prostacyclin pathway and by improving nitric oxide bioavailability. Aggressive cancer cell lines are reported to have higher levels of MNA due to increased NNMT-directed transfer of methyl groups from S-adenosyl-L-methionine to nicotinamide, implicating a role for MNA in cancer cell metabolism.
Uses	1-Methylnicotinamide chloride may be used as a standard in the quantification of 1-methylnicotinamide in urine samples using ion pairing reverse-phase high performance liquid chromatography (RP-HPLC).
Uses	Nicotinamide is a precursor of NAD and NADP , which serve essential functions in modulating cellular redox status and controlling signaling and transcriptional events. 1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced by the action of nicotinamide N-methyltransferase (NNMT; ). It demonstrates antithrombotic and anti-inflammatory properties through direct action on the endothelium by a mechanism involving the prostacyclin pathway and by improving nitric oxide bioavailability. Aggressive cancer cell lines are reported to have higher levels of MNA due to increased NNMT-directed transfer of methyl groups from S-adenosyl-L-methionine to nicotinamide, implicating a role for MNA in cancer cell metabolism.
General Description	1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced mainly by nicotinamide N-methyltransferase (NNMT) and exhibits antithrombotic and anti-inflammatory effects.
Biochem/physiol Actions	1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced mainly by nicotinamide N-methyltransferase (NNMT). 1-Methylnicotinamide (MNA) has been shown to have antithrombotic and anti-inflammatory effects. A recent study indicated that MNA may exert antithrombotic and anti-inflammatory effects through direct action on the endothelium, with a vasorelaxing effect by enhancement of NO bioavailability and reduction of eNOS-dependent oxidative stress. Enhanced NNMT activity is a feature of many types of cancer. How much direct involvement MNA has in the tumorigenesis associated with overexpression of NNMT is under investigation. MNA by itself increased mitochondrial Complex I activity and increased cancer cell viability in SH-SY5Y neuroblastoma cells that do not produce NNMT.
Purification Methods	Recrystallise it from MeOH. [Beilstein 22 III/IV 468, 22/2 V 80.]
References	[1] THEODORE A. ALSTON Robert H A. Substrate specificity of nicotinamide methyltransferase isolated from porcine liver[J]. Archives of biochemistry and biophysics, 1988, 260 2: Pages 601-608. DOI: 10.1016/0003-9861(88)90487-0 [2] TERESA B DOMAGALA. Nitric oxide production and endothelium-dependent vasorelaxation ameliorated by N1-methylnicotinamide in human blood vessels.[J]. Hypertension, 2012, 59 4: 825-832. DOI: 10.1161/hypertensionaha.111.183210 [3] S CHLOPICKI. 1-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathway[J]. British Journal of Pharmacology, 2009, 152 2: 230-239. DOI: 10.1038/sj.bjp.0707383

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ECHEMI Editorial Reference

White powder. Melting point 121°C. Stable in air. Insoluble in water. A female sex hormone. Low toxicity.
Steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.

Basic Info

Product Name:

Progesterone

Other Name:

Pregn-4-ene-3,20-dione;Progesterone;Corlutin;Corlutina;Corluvite;Corporin;Corpus luteum hormone;Flavolutan;Fologenon;Gestone;Gestormone;Glanducorpin;Hormoflaveine;Hormoluton;Luteal Hormone;Luteinique;Luteodyn;Luteogan;Luteohormone;Luteosan;Luteostab;Luteovis;Lutex;Lutidon;Lutocyclin;Lutocyclin M;Lutocylin;Lutoform;Lutogyl;Lutren;Lutromone;Piaponon;Primolut;Progekan;Progesterol;Progestin;Progestone;Prolidon;Luteol;Syntolutan;Proluton;Agolutin;Lucorteum Sol;Gestron;Percutacrine Luteinique;Lipo-Lutin;Nalutron;Progestron;Luteopur;Bio-luton;Gynlutin;Gynolutone;Gesterol;Luteocrin normale;Syngestrets;Prolets;Lutin;Lutociclina;Protormone;Progestasert;Vitarrine;Δ4-Pregnene-3,20-dione;Utrogestan;Luteum;U 3672;Crinone;Progestogel;Lugesteron;Prontogest;Prometrium;Utrogest;Cyclogest;Syngesterone;Progestol;Gestiron;Lutocuclin M;Progeston;NSC 64377;NSC 9704;Progeffik;Progestan;Duraprogen;CIDR;Estima;Prochieve;Endometrin;Minagest;Microgest;Lugesterone;EAZI-BREED CIDR;4-Pregnene-3,20-dione;P4;Luteosterone;Sincrogest;Lutinus;Cue-Mate;Progeffik 200;8012-32-6;8023-13-0;257630-50-5;753497-20-0;2051138-40-8

CAS No.:

57-83-0

Molecular Formula:

C21H30O2

InChIKeys:

InChIKey=RJKFOVLPORLFTN-LEKSSAKUSA-N

Molecular Weight:

314.46200

Exact Mass:

314.46

EC Number:

200-350-6

HScode:

29372390

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

34.14000

XLogP3:

4.72350

Appearance:

Progesterone is a white powder. Melting point 121°C. Stable in air. Insoluble in water. A female sex hormone. Low toxicity.

Density:

1.166 g/cm³ @ Temp: 23 °C

Melting Point:

127-131 °C

Boiling Point:

447.2ºC at 760mmHg

Flash Point:

166.7ºC

Refractive Index:

182 ° (C=2, Dioxane)

Water Solubility:

H2O: 0.00881 mg/mL at 25 °C

Storage Conditions:

Store in a cool, dry place. Store in a tightly closed container. Hormones and antibiotics room.

Vapor Pressure:

3.59X10-4 mm Hg at 25 deg C (est)

Toxicity:

LD50 intraperitoneal in rat: 327mg/kg

Specific rotation:

Specific optical rotation: +172 to +182 deg at 20 °C/D (c = 2 in dioxane)

Odor:

Odorless

PKA:

Strongest acidic: , Strongest basic: 18.92, -4.8

See More Progesterone Properties 

Hazard Identification

Classification of the substance or mixture

Carcinogenicity, Category 2

Reproductive toxicity, Category 1B

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H351 Suspected of causing cancer H360 May damage fertility or the unborn child
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Parenteral progesterone preparations, progesterone capsules, progesterone vaginal inserts, and progesterone vaginal gel should be stored at 15-30 deg C.

See More Progesterone Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10 days

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

21 Inquiries

Country	Product	Purchase Quantity	Date Posted
Germany	Pharmaceutical grade micronized Progesterone	200 G	Feb 27, 2024
Portugal	bioidentical progesterone	25 KG	Oct 22, 2026
United States	Progesterone	100 G	Oct 2, 2026
Lithuania	progesterone	10 G	Sep 8, 2026
United States	Progesterone	5 KG	May 12, 2026
United States	progesterone	200 G	Nov 20, 2025
India	Progesterone	10 MG	Oct 21, 2025
Pakistan	PROGESTERONE MICRONIZED	230 KG	Jul 22, 2025
India	Progesterone	500 KG	Jul 3, 2025
United States	Progesterone 99% white powder USP	25 KG	Mar 6, 2025
Algeria	Progesterone	10 KG	Feb 27, 2025
United States	Progesterone	30 G	Sep 11, 2024
United States	progesterone	1 KG	Sep 9, 2024
Germany	Progesterone	500 G	Oct 16, 2026
Australia	Progesterone	10 KG	Mar 24, 2026
United Arab Emirates	Progesterone	2000 KG	Jan 12, 2026
India	Progesterone powder	1.00 KG	Jul 31, 2024
Portugal	Progesterone	25 KG	Oct 22, 2026
United States	Progesterone	200 G	Sep 30, 2026
United States	progesterone	1 KG	May 29, 2026

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Progesterone 57-83-0 200-350-6

Product Details

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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