Diazolidinyl urea
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Diazolidinyl urea
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CAS No:
78491-02-8
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Formula:
C8H14N4O7
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Chemical Name:
Diazolidinyl urea
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Synonyms:
Urea,N-[1,3-bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-N,N′-bis(hydroxymethyl)-;N-[1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-N,N′-bis(hydroxymethyl)urea;Germall II;Diazolidinyl urea;Germaben II-E;N-Hydroxymethyl-N-[1,3-di(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-N′-hydroxymethylurea;1-[1,3-Bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea;Diazolidinylurea
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CAS No:
Characteristics
153.88000
-2.5
white powder, free-flowing
1.83 g/cm3
1.587
2-8ºC
LD50 orally in rats: 2.57 g/kg; dermally in rabbits: >2.0 g/kg (Berke, Rosen)
Safety Information
NONH for all modes of transport
2
R43
S36/37
YS2717000
Xi
Stable. Incompatible with strong oxidizing agents.
P280
H317
|Warning|H317 (51.13%): May cause an allergic skin reaction [Warning Sensitization, Skin]|P261, P264, P272, P273, P280, P302+P352, P305+P351+P338, P321, P333+P313, P337+P313, P363, and P501|Aggregated GHS information provided by 1104 companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H315: Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P272, P280, P302+P352, P305+P351+P338, P321, P332+P313, P333+P313, P337+P313, P362, P363, and P501
Diazolidinyl urea Use and Manufacturing
Diazolidinyl urea is an antimicrobial preservative used in cosmetics. It is chemically related to imidazolidinyl urea which is used in the same way. Diazolidinyl urea acts as a formaldehyde releaser.It is used in many cosmetics, skin care products, shampoos and conditioners, as well as a wide range of products including bubble baths, baby wipes and household detergents. Diazolidinyl urea is found in the commercially available preservative Germaben.Commercial diazolidinyl urea is a mixture of different formaldehyde addition products including polymers.
Urea, N-[1,3-bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-N,N'-bis(hydroxymethyl)-: ACTIVE
Cosmetics -> Preservative
Computed Properties
Molecular Weight:278.22
XLogP3:-2.5
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:278.08624880
Monoisotopic Mass:278.08624880
Topological Polar Surface Area:154
Heavy Atom Count:19
Complexity:376
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
antimicrobial agent; releases formaldehyde as a preservative
Registered Holders
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INTERNATIONAL SPECIALTY PRODUCTS, LTD.
Inactive
United States
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SUTTON LABORATORIES
Inactive
United States
Recommended Suppliers of Diazolidinyl urea
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Business licensedTrader Supplier of pharmaceutical intermediates,excipients,plant extracts,food additives,CDMO,fine cheimcals,Octadecanedioic acid,Eicosanedioic AcidInquiryCAS No.: 78491-02-8Grade: Pharmaceutical GradeContent: 99% -
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Business licensedTrader Supplier of pharmaceutical raw materials, pharmaceutical intermediates, basic chemicals and agrochemicalsInquiryCAS No.: 78491-02-8Grade: Chemical Grade -
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Business licensedTrader Supplier of germall 115,bit,allantoin,bronopol,dmdmh,germall a,germall plus,cmit/mit,germaben b,mit,dmdmh plusInquiryUnit Price: $7.9-8.89 /KG FOBCAS No.: 78491-02-8Grade: Cosmetics GradeContent: 99%
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