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Imidazolidinyl urea

Imidazolidinyl urea structure

CAS No:
39236-46-9
Formula:
C11H16N8O8
Chemical Name:
Imidazolidinyl urea
Synonyms:
Urea,N,N′′-methylenebis[N′-[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-;N,N′′-Methylenebis[N′-[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]urea];Germall 115;Imidazolidinyl urea;Biopure 100;Euxyl K 200;Imidurea;Abiol;Sepicide CI;Kemipur 100;Bis(methylol) imidazolidinyl urea;1-[3-(Hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-3-[[[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]carbamoylamino]methyl]urea;1,1′-Methylenebis(3-(3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl)urea);82852-50-4;1698942-49-2
Categories:
Cosmetic Ingredient > Cosmetic Preservative

Description

Imidazolidinyl urea is an antimicrobial preservative used in cosmetics, acts as a formaldehyde releaser.

Imidurea is a member of ureas. It has a role as an antimicrobial agent.|Imidurea is an antimicrobial preservative used in cosmetics. It acts as a formaldehyde releaser.|Imidurea is a Standardized Chemical Allergen. The physiologic effect of imidurea is by means of Increased Histamine Release, and Cell-mediated Immunity.

Imidazolidinyl urea Basic Attributes

Molecular Weight：

388.29400

Exact Mass：

388.29

EC Number：

254-372-6

UNII：

M629807ATL

DSSTox ID：

DTXSID2040151

HScode：

2933290090

Characteristics

PSA：

221.54000

XLogP3：

-3.4

Appearance：

white fluid powder, with slight characteristic odor.

Density：

1.85g/cm3

Melting Point：

141-143℃

Refractive Index：

1.714

Water Solubility：

H2O: soluble

Storage Conditions：

2-8ºC

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

R36

safety instructions：

S26-S36

RTECS Number：

YT7365000

Marks：

Stability/Shelf Life：

Stable.

Precautionary statement(s)：

P305 + P351 + P338

Hazard Statements：

H319

GHS Classification：

|Warning|H317 (88.76%): May cause an allergic skin reaction [Warning Sensitization, Skin]|P261, P264, P272, P280, P302+P352, P305+P351+P338, P321, P333+P313, P337+P313, P363, and P501|Aggregated GHS information provided by 555 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H315: Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P272, P280, P302+P352, P305+P351+P338, P321, P332+P313, P333+P313, P337+P313, P362, P363, and P501

Drug Information

MeSH Entry Terms：

Germall 115

Imidazolidinyl urea Use and Manufacturing

Uses

Antimicrobial preservative in cosmetics and topical pharmaceutical preparations.

Manufacturing Info：

Urea, N,N''-methylenebis[N'-[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-: ACTIVE

Use Classification：

Cosmetics -> Preservative

Computed Properties

Molecular Weight:388.29
XLogP3:-3.4
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:6
Exact Mass:388.10910950
Monoisotopic Mass:388.10910950
Topological Polar Surface Area:222
Heavy Atom Count:27
Complexity:627
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Formaldehyde-releasing preservative, provides broad-spectrum antimicrobial protection

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

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Registered Holders

Wuhu Huahai Biology Technology Co., Ltd.

China
Active
Dongguan Dongyue Glucose Factory Co., Ltd.

China
Inactive
SUTTON LABORATORIES

United States
Inactive

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39236-46-9 1-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-3-[[[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]carbamoylamino]methyl]urea

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