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1-Benzothiophen-5-amine

1-Benzothiophen-5-amine structure

CAS No:
20532-28-9
Formula:
C8H7NS
Chemical Name:
1-Benzothiophen-5-amine
Synonyms:
IFLAB-BB F0817-0001;BENZO[B]THIOPHEN-5-YLAMINE;5-AMINOBENZOTHIOPHENE;1-BENZOTHIOPHEN-5-AMINE;1-Benzothiophen-5-amine, 95+%;benzothiophen-5-amine;1-BENZOTHIEN-5-YLAMINE HYDROCHLORIDE;5-Aminobenzothiophen
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

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1-Benzothiophen-5-amine Basic Attributes

Molecular Weight：

149.21

Exact Mass：

149.029922

NSC Number：

148327

DSSTox ID：

DTXSID40302075

HScode：

2934999090

Characteristics

PSA：

54.3

XLogP3：

3.06470

Appearance：

white crystals

Density：

1.3±0.1 g/cm3

Melting Point：

72 °C

Boiling Point：

369.5°C at 760 mmHg

Flash Point：

143.2±20.4 °C

Refractive Index：

1.744

Vapor Pressure：

5.56E-06mmHg at 25°C

Safety Information

hazard class code：

safety instructions：

24/25

Marks：

1-Benzothiophen-5-amine Use and Manufacturing

Methods of Manufacturing

A mixture of 5-nitrobenzo[b]thiophene (3.09 g, 17.0 mmol) and 10percent palladium on carbon (Aldrich, cat. No. 20, 569-9) (150 mg) in ethanol (90 mL) was shaken in a Parr flask under a hydrogen atmosphere of 3 bar. After 16 h the catalyst was filtered off over a celite pad and washed with ethanol (2 x 30 mL). The filtrate was evaporated in vacuo to yield benzo[b]thiophen-5-amine (2.57 g, 100percent) as a dark purple amorphous solid.

Uses

For the synthesis of liquid crystal monomers

Computed Properties

Molecular Weight:149.21
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Exact Mass:149.02992040
Monoisotopic Mass:149.02992040
Topological Polar Surface Area:54.3
Heavy Atom Count:10
Complexity:126
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Sodium hydroxide

Hydrogen

Ethanol

Acetone

Hydrochloric acid

Sodium chloride

PETROLEUM ETHER

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1-Benzothiophen-5-amine

CAS No.: 20532-28-9

Content: 99.00%

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Compound Net Biotechnology Inc. Contact Supplier

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20532-28-9 1-benzothiophen-5-amine

CAS No.: 20532-28-9

Grade: Industrial Grade

Content: 95%

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