α-Ethyl-2-oxo-1-pyrrolidineacetamide
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α-Ethyl-2-oxo-1-pyrrolidineacetamide
structure -
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CAS No:
33996-58-6
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Formula:
C8H14N2O2
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Chemical Name:
α-Ethyl-2-oxo-1-pyrrolidineacetamide
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Synonyms:
1-Pyrrolidineacetamide,α-ethyl-2-oxo-;α-Ethyl-2-oxo-1-pyrrolidineacetamide;Etiracetam;UCB 6474;2-(2-Oxopyrrolidin-1-yl)butanamide;2-(2-Oxo-1-pyrrolidinyl)butanamide;103833-73-4
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CAS No:
Description
Etiracetam (UCB 6474) is an acetylcholine agonist and a nootropic drug of the racetam family. Less active than its S-enantiomer Levetiracetam (UCB L059)[1].
Etiracetam is an organooxygen compound.|Etiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)).|A pyrrolidinone and acetamide derivative that is used primarily for the treatment of SEIZURES and some movement disorders, and as a nootropic agent.
α-Ethyl-2-oxo-1-pyrrolidineacetamide Basic Attributes
170.21
170.21
446-650-2
DTXSID5046510
2933790002
Characteristics
63.4
-0.67
1.2±0.1 g/cm3
113-114 °C @ Solvent: Acetone
395.9±25.0 °C at 760 mmHg
193.2±23.2 °C
1.519
Safety Information
UN 3077 9 / PGIII
22-36-51/53
26-61
Xn,N
P273-P305 + P351 + P338
H302-H319-H411
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P273, P280, P301+P312, P305+P351+P338, P330, P337+P313, P391, and P501|Aggregated GHS information provided by 40 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms. (See all compounds classified as Nootropic Agents.)|Drugs used to prevent SEIZURES or reduce their severity. (See all compounds classified as Anticonvulsants.)
alpha ethyl 2 oxo 1 Pyrrolidineacetamide
α-Ethyl-2-oxo-1-pyrrolidineacetamide Use and Manufacturing
A nootropic drug that produced a significant increase in β-wave activity and stimulated α-wave activity dose-dependently. It has been used in studies to alleviate the effects of memory retrieval deficits in rats.
Computed Properties
Molecular Weight:170.21
XLogP3:-0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:170.105527694
Monoisotopic Mass:170.105527694
Topological Polar Surface Area:63.4
Heavy Atom Count:12
Complexity:203
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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α-Ethyl-2-oxo-1-pyrrolidineacetamide
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