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Calcifediol

Calcifediol structure

CAS No:
63283-36-3
Formula:
C27H44O2
Chemical Name:
Calcifediol
Synonyms:
Calcifediol /25-Dihydroxyvitamin D3;25-OH-VD3;Calcifediol/25-Hydroxycholecalciferol H20;CALCIDIOL;CALCIFEDIOL;CALCIFEDIOL MONOHYDRATE;25-OH-D3;25-HYDROXYVITAMIN D3
Categories:
Active Pharmaceutical Ingredients > Vitamins and Minerals Medicines

Description

Calcifediol (monohydrate) is a major circulating metabolite of vitamin D3, acting as a competitive inhibitor with an apparent Ki of 3.9 μM, suppresses PTH secretion and mRNA (ED50=2 nM).

Calcifediol Basic Attributes

Molecular Weight：

400.64

Exact Mass：

418.344695 g/mol

EC Number：

242-990-9

HScode：

29362900

Characteristics

PSA：

40.46000

XLogP3：

6.73390

Appearance：

brownish, fine powder

Boiling Point：

529.2ºC at 760 mmHg

Flash Point：

14℃

Storage Conditions：

−20°C

Vapor Pressure：

2.07E-13mmHg at 25°C

Safety Information

Transport codes：

UN 2811 6.1/PG 2

wgk germany：

hazard class code：

28-48/25-26-24/25

safety instructions：

28-36/37-45

Marks：

T+

Precautionary statement(s)：

P210-P280-P305 + P351 + P338-P337 + P313-P403 + P235

Hazard Statements：

H225-H319

Calcifediol Use and Manufacturing

Calcifediol is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It is produced in the liver and is the best indicator of the body’s vitamin D stores. It is effective in the treatment of ricket

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