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(+)-Lansoprazole

(+)-Lansoprazole structure

CAS No:
138530-94-6
Formula:
C16H14F3N3O2S
Chemical Name:
(+)-Lansoprazole
Synonyms:
1H-Benzimidazole,2-[(R)-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-;1H-Benzimidazole,2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-,(R)-;2-[(R)-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole;(+)-Lansoprazole;R-(+)-Lansoprazole;(R)-2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole;(R)-2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole;Dexlansoprazole;(R)-Lansoprazole;T 168390;TAK 390;Dexilant;Dextrolansoprazole;(+)-Lansoprazol;2-[(R)-[3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1H-benzimidazole;1336907-93-7
Categories:
Active Pharmaceutical Ingredients > Digestive System Drugs

Description

Brown SolidThe mechanism of PPIs involves the irreversible binding to the hydrogen/potassium adenosine triphosphatase enzyme system, commonly referred to as the gastric proton pump, of the gastric parietal cell. As the last stage in gastric acid secretion, blockade of the gastric proton pump is an effective treatment for a variety of diseases requiring acid suppression, such as heartburn, peptic ulcers, and GERD. Dexlansoprazole is the latest PPI to hit the market, joining the ranks of omepr

(+)-Lansoprazole Basic Attributes

Molecular Weight：

369.36

Exact Mass：

369.36

EC Number：

1308068-626-2

Characteristics

PSA：

87.1

XLogP3：

2.8

Appearance：

Brown solid

Density：

1.50±0.1 g/cm3(Predicted)

Melting Point：

66-68°C

Boiling Point：

555.8±60.0 °C(Predicted)

Flash Point：

289.9±32.9 °C

Refractive Index：

1.635

Water Solubility：

H2O: 0.21mg/mL at pH7.0

Storage Conditions：

Refrigerator

PKA：

8.87None

(+)-Lansoprazole Use and Manufacturing

The R-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative

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