 Home > Encyclopedia > Risperidone

Risperidone

Risperidone structure

CAS No:
106266-06-2
Formula:
C23H27FN4O2
Chemical Name:
Risperidone
Synonyms:
4H-Pyrido[1,2-a]pyrimidin-4-one,3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-;1,2-Benzisoxazole,4H-pyrido[1,2-a]pyrimidin-4-one deriv.;3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one;Risperidone;R 64766;Risperdal;Spiron;Rispadal;Risperidal;Apexidone;Psychodal;Risperdal Consta;Ripedon;3-[2-[4-(6-Fluor-1,2-benzisoxazol-3-yl)piperidino]ethyl]-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-on;Risperdine;Zophrenal;Risperid fort;Risperid;RBP 7000;Risperidone ACIS;Risbiodal;Rispa
Categories:
Active Pharmaceutical Ingredients > Nervous System Drugs

Description

Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively.

Risperidone Basic Attributes

Molecular Weight：

410.48

Exact Mass：

410.48

EC Number：

1806241-263-5

HScode：

2934999090

Characteristics

PSA：

61.9

XLogP3：

2.7

Appearance：

Solid

Density：

1.4±0.1 g/cm3

Melting Point：

170 °C

Boiling Point：

442

Flash Point：

9℃

Refractive Index：

1.677

Water Solubility：

DMSO: ≥5mg/mL

Storage Conditions：

room temp

Vapor Pressure：

4.6X10-11 mm Hg at 25 deg C (est)

Safety Information

Packing level：

Ⅲ

Hazard category：

6.1(a)

Transport codes：

3249

hazard class code：

25-39/23/24/25-23/24/25-11

safety instructions：

28-36-45-36/37-16

RTECS Number：

UV1164800

Marks：

T,F

Stability/Shelf Life：

Stable under recommended storage conditions.

Precautionary statement(s)：

P210-P260-P280-P301 + P310-P311

Hazard Statements：

H225-H301 + H311 + H331-H370

Risperidone Use and Manufacturing

A combined serotonin (5-HT2) and dopamine (D2) receptor antagonist It has 5HT2 receptor and D2 receptor antagonism. Used for acute and chronic schizophrenia. Antipsychotics

Computed Properties

Molecular Weight:410.5
XLogP3:2.7
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:410.21180428
Monoisotopic Mass:410.21180428
Topological Polar Surface Area:61.9
Heavy Atom Count:30
Complexity:731
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Potassium iodide

Drug Function and Efficacy

Extract from the above information

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Risperidone Microspheres for Injection
Specifications	25mg

Risperidone tablets
Ingredients	Risperidone, chemical name 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Indication	1 This product can antagonize the effects of levodopa and other dopamine agonists. 2 Carbamazepine and other liver enzyme inducers will reduce the plasma concentration of the active ingredient of this product. Once carbamazepine or other liver enzyme inducers are stopped, the dosage of this product should be re-determined and reduced if necessary. 3 Phenothiazines, tricyclic antidepressants and some beta-blockers will increase the blood concentration of this product, but will not increase the blood concentration of the antipsychotic active ingredient. 4 When taken together with other highly protein-bound drugs, there is no clinically significant mutual replacement of plasma proteins.
Specifications	1mg
Manufacturer	Tipr Pharmaceutical Co., Ltd.

Risperidone Microspheres for Injection
Specifications	50mg

See More Related Drugs

Registered Holders

JUBILANT BIOSYS LTD

United States
Active
MATRIX PHARMACORP PRIVATE LTD

United States
Active
APITORIA PHARMA PRIVATE LTD

United States
Active

See More Registered Holders

Recommended Suppliers of Risperidone

Hangzhou Hyper Chemicals Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

99% Assay Risperidone CAS 106266-06-2 White Raw Powder with Fast Delivery

CAS No.: 106266-06-2

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Echemi Pharmaceutical Contact Supplier

CN
8 YRS

Business licensed

Distributor Supplier of API,Intermediate

Risperidone-ECHEMI

CAS No.: 106266-06-2

Grade: Pharmaceutical Grade

Inquiry
Hangzhou Chungyo Chemicals Co., Ltd. Contact Supplier

CN
3 YRS

Business licensed Certified factory

Manufactory Supplier of Dyes,Textile agent,Medical intermediate,API,Pigments,Basic Chemicals

Risperidone

CAS No.: 106266-06-2

Grade: Industrial Grade

Content: 99%

Inquiry
Shandong Airuike Chemical Co., Ltd. Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals,CATALYST AND AUXILIARY,FLAVORS AND FRAGRANCES,Chemical Pesticides,ADDITIVE

Risperidone CAS 106266-06-2

CAS No.: 106266-06-2

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Shanghai Lonwin Chemical Co.,Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of CHEMICALS,REAGENTS

High quality Risperidal CAS NO.106266-06-2

CAS No.: 106266-06-2

Grade: Pharmaceutical Grade

Content: 99%

Inquiry