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Ibandronate sodium

Ibandronate sodium structure

CAS No:
138844-81-2
Formula:
C9H23NO7P2.Na
Chemical Name:
Ibandronate sodium
Synonyms:
Phosphonic acid,P,P′-[1-hydroxy-3-(methylpentylamino)propylidene]bis-,sodium salt (1:1);Phosphonic acid,[1-hydroxy-3-(methylpentylamino)propylidene]bis-,monosodium salt;BM 21.0955;Bonviva;BM 21.0955Na;Bondronat;Ibandronate sodium;Bondronate;Boniva;1296822-62-2
Categories:
Active Pharmaceutical Ingredients > Fluid, Electrolyte, and Acid-base Balance

Description

Ibandronate Sodium is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.Target: OthersIbandronate (1.25-2 μM) significantly reduces endothelial cell growth, while ibandronate (2 μM) also significantly reduces capillary-like tube formation and increases apoptosis of endothelial cells. Ibandronate (< 100 μM) dose-dependently increases VEGF expression in endothelial cells [1]. Ibandronate (< 100 μM) inhibits growth of both prostate cancer cell lines (

Ibandronate sodium Basic Attributes

Molecular Weight：

341.21

Exact Mass：

341.076904

EC Number：

1308068-626-2

HScode：

29319090

Characteristics

PSA：

141

XLogP3：

0.93820

Boiling Point：

587.8ºC at 760 mmHg

Flash Point：

309.3ºC

Water Solubility：

H2O: >10mg/mL

Storage Conditions：

2-8°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

RTECS Number：

SZ8563300

Precautionary statement(s)：

P260, P264, P270, P273, P301+P312, P309+P311, P314, P330, P391, P405, P501

Hazard Statements：

H302

Drug Function and Efficacy

Extract from the above information

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Ibandronate
Specifications	API
Manufacturer	Yabao PHARMA Sichuan Pharmaceutical Co., Ltd.

Ibandronate
Ingredients	Main ingredients: Ibandronate sodium. Excipients: Sodium chloride, acetic acid, sodium acetate, water for injection
Specifications	API
Manufacturer	Nanjing Hencer Pharmaceutical Co., Ltd.

Ibandronate Sodium Injection
Ingredients	Active ingredient: Ibandronate sodium.
Indication	When this product is used together with aminoglycosides, it may cause a prolonged decrease in blood calcium levels and hypomagnesemia, so extreme caution should be exercised. No studies on the interaction between this product and other drugs have been conducted.
Specifications	1ml:1mg (calculated as ibandronic acid)
Manufacturer	Sichuan Meida Kangjiale Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

ORBION PHARMACEUTICALS PRIVATE LTD

United States
Active
APITORIA PHARMA PRIVATE LTD

United States
Active
APOTEX INC

Brazil
Active

See More Registered Holders

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