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Oxiracetam

Oxiracetam structure

CAS No:
62613-82-5
Formula:
C6H10N2O3
Chemical Name:
Oxiracetam
Synonyms:
1-Pyrrolidineacetamide,4-hydroxy-2-oxo-;4-Hydroxy-2-oxo-1-pyrrolidineacetamide;Oxiracetam;ISF 2522;Hydroxypiracetam;CT 848;CGP 21690;Neuractiv;Neuromet;CGP 21690E;2-(4-Hydroxy-2-oxopyrrolidin-1-yl)acetamide;4-Hydroxypyrrolidone-2-acetamide;Oxyracetam;68567-97-5
Categories:
Active Pharmaceutical Ingredients > Nervous System Drugs

Description

Oxiracetam is a cyclic derivative of γ-aminobutyric acid (GABA) which has been commonly used as nootropic drug to treat cognitive impairments.

Oxiracetam is an organooxygen compound and an organonitrogen compound. It derives from an alpha-amino acid.

Oxiracetam Basic Attributes

Molecular Weight：

158.16

Exact Mass：

158.16

EC Number：

2017-001-1

UNII：

P7U817352G

DSSTox ID：

DTXSID9045180

ATC Code：

N - Nervous system

HScode：

2933790090

Characteristics

PSA：

83.6

XLogP3：

-2.2

Appearance：

white crystalline powder

Density：

1.416

Melting Point：

165-168 °C

Boiling Point：

494.6ºC at 760 mmHg

Flash Point：

252.9±27.3 °C

Refractive Index：

1.570

Storage Conditions：

2-8°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/38

safety instructions：

26-36

RTECS Number：

UX9656638

Marks：

Precautionary statement(s)：

P305 + P351 + P338

Hazard Statements：

H315-H319

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH：

A loosely defined grouping of drugs that have effects on psychological function. Here the psychotropic agents include the antidepressive agents, hallucinogens, and tranquilizing agents (including the antipsychotics and anti-anxiety agents). (See all compounds classified as Psychotropic Drugs.)|Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms. (See all compounds classified as Nootropic Agents.)

MeSH Entry Terms：

ISF 2522

Oxiracetam Use and Manufacturing

It is a derivative of Piracetam, has central excitatory effect, can promote brain metabolism, significantly improve and promote brain memory, and is effective for senile memory and mental decline. Most of this product is excreted in the urine as a prototype drug after taking it, does not accumulate in the body, is well absorbed, and is well tolerated. It is used for the elderly with cerebral insufficiency and memory loss, especially for Alzheimer's disease, but also for the rehabilitation of neurosis, brain injury, encephalitis and other brain diseases. Intelligence promoting medicine, used for senile brain insufficiency syndrome, mental behavior disorder, etc. Oxiracetam is an analogue of Piracetam, which can improve the memory and learning function of patients with Alzheimer's disease and memory disorders. This product is an analogue of Piracetam, which can improve the memory and learning function of patients with Alzheimer's disease and memory disorders.

Computed Properties

Molecular Weight:158.16
XLogP3:-2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:158.06914219
Monoisotopic Mass:158.06914219
Topological Polar Surface Area:83.6
Heavy Atom Count:11
Complexity:192
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Extract from the above information

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

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Ingredients	Oxiracetam.
Indication	Not yet clear.
Specifications	5ml:1g
Manufacturer	Harbin Medisan Pharmaceutical Co., Ltd.

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Registered Holders

BrightGene Pharmaceutical Co., Ltd.

China
Active
Reyoung Pharmaceutical Co., Ltd.

China
Active
Kaiyuan Hengtai Pharma Co., Ltd.

China
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