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Home > Encyclopedia > 4-CHLORO-6-METHYLTHIOPYRIMIDINE

4-CHLORO-6-METHYLTHIOPYRIMIDINE

4-CHLORO-6-METHYLTHIOPYRIMIDINE structure

4-CHLORO-6-METHYLTHIOPYRIMIDINE 

structure
  • CAS No:

    89283-48-7

  • Formula:

    C5H5ClN2S

  • Chemical Name:

    4-CHLORO-6-METHYLTHIOPYRIMIDINE

  • Synonyms:

    4-Chloro-6-methylthiopyrimidine;4-CHLORO-6-(METHYLTHIO)PYRIMIDINE;4-chloro-6-methylsulfanylpyrimidine;4-chloro-6-(methylsulfanyl)pyrimidine;Pyrimidine, 4-chloro-6-(methylthio)-;Pyrimidine,4-chloro-6-(methylthio)-;ACMC-20a064;SCHEMBL1660128;CTK5G2779;DTXSID50618311

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

4-CHLORO-6-METHYLTHIOPYRIMIDINE Basic Attributes

160.62

159.986191

DTXSID50618311

2933599090

Characteristics

51.1

2

1.37

50-51 °C

260 ºC

111 ºC

1.595

Safety Information

NONH for all modes of transport

3

43

36/37

P280

H302-H317

4-CHLORO-6-METHYLTHIOPYRIMIDINE Use and Manufacturing

Synthesis of 6-methyl-3-(6-(methylsuIfmyl)pyrimidin-4- vI)pyrazolori, 5-a]pyrimidin-2-amine EPO Example 20; l-{4-[6-(2-Hydroxy-ethylamino)-pyrimidin-4-yloxy]-phenyl}-3-(3- trifluoromethyl-phenyl)-ureai) 4-Chloro-6-methylsulfanyl-pyrimidine To a solution of 4, 6-dichloro-pyrimidine (10.0 g, 67 mmol) in THF (55 ml), sodium thiomethylate (5.175 g, 74 mmol) is added under inert gas atmosphere. The reaction mixture is stirred at 60

Computed Properties

Molecular Weight:160.63
XLogP3:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:159.9861970
Monoisotopic Mass:159.9861970
Topological Polar Surface Area:51.1
Heavy Atom Count:9
Complexity:91
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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