4-CHLORO-6-METHYLTHIOPYRIMIDINE
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4-CHLORO-6-METHYLTHIOPYRIMIDINE
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CAS No:
89283-48-7
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Formula:
C5H5ClN2S
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Chemical Name:
4-CHLORO-6-METHYLTHIOPYRIMIDINE
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Synonyms:
4-Chloro-6-methylthiopyrimidine;4-CHLORO-6-(METHYLTHIO)PYRIMIDINE;4-chloro-6-methylsulfanylpyrimidine;4-chloro-6-(methylsulfanyl)pyrimidine;Pyrimidine, 4-chloro-6-(methylthio)-;Pyrimidine,4-chloro-6-(methylthio)-;ACMC-20a064;SCHEMBL1660128;CTK5G2779;DTXSID50618311
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CAS No:
4-CHLORO-6-METHYLTHIOPYRIMIDINE Use and Manufacturing
Synthesis of 6-methyl-3-(6-(methylsuIfmyl)pyrimidin-4- vI)pyrazolori, 5-a]pyrimidin-2-amine EPO Example 20; l-{4-[6-(2-Hydroxy-ethylamino)-pyrimidin-4-yloxy]-phenyl}-3-(3- trifluoromethyl-phenyl)-ureai) 4-Chloro-6-methylsulfanyl-pyrimidine To a solution of 4, 6-dichloro-pyrimidine (10.0 g, 67 mmol) in THF (55 ml), sodium thiomethylate (5.175 g, 74 mmol) is added under inert gas atmosphere. The reaction mixture is stirred at 60
Computed Properties
Molecular Weight:160.63
XLogP3:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:159.9861970
Monoisotopic Mass:159.9861970
Topological Polar Surface Area:51.1
Heavy Atom Count:9
Complexity:91
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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