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Home > Encyclopedia > 2-Bromo-4-methoxypyridine

2-Bromo-4-methoxypyridine

2-Bromo-4-methoxypyridine structure

2-Bromo-4-methoxypyridine 

structure
  • CAS No:

    89488-29-9

  • Formula:

    C6H6BrNO

  • Chemical Name:

    2-Bromo-4-methoxypyridine

  • Synonyms:

    2-Bromo-4-methoxypyridine;PYRIDINE, 2-BROMO-4-METHOXY-;PubChem5957;4-methoxy-2-bromopyridine;ACMC-209r1g;Pyridine,2-bromo-4-methoxy-;SCHEMBL451020;2-bromanyl-4-methoxy-pyridine;CTK5G3191;KS-00000DWN

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

2-Bromo-4-methoxypyridine Basic Attributes

188.02

186.963272

DTXSID70406217

2933399090

Characteristics

22.1

1.8

1.5±0.1 g/cm3

231.1°C at 760 mmHg

93.5±21.8 °C

1.543

Safety Information

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, P501

H302

|Warning|H302 (66.67%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 3 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

2-Bromo-4-methoxypyridine Use and Manufacturing

To a solution of 2-bromo-4-chloropyridine (1.0 g, 5.2 mmol) in DMSO (10 mL) was added sodium methanolate (0.35 g, 6.48 mmol). After the addition, the mixture was stirred at 120 °C for 24 h. The reaction was cooled to rt and extracted with EtOAc. The combined organic layers were dried (Na

Computed Properties

Molecular Weight:188.02
XLogP3:1.8
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:186.96328
Monoisotopic Mass:186.96328
Topological Polar Surface Area:22.1
Heavy Atom Count:9
Complexity:89.1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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