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Eprazinone

Eprazinone structure

Eprazinone 

structure
  • CAS No:

    10402-90-1

  • Formula:

    C24H32N2O2

  • Chemical Name:

    Eprazinone

  • Synonyms:

    1-Propanone,3-[4-(2-ethoxy-2-phenylethyl)-1-piperazinyl]-2-methyl-1-phenyl-;3-[4-(2-Ethoxy-2-phenylethyl)-1-piperazinyl]-2-methyl-1-phenyl-1-propanone;Eprazinone

  • Categories:

    Active Pharmaceutical Ingredients  >  Respiratory Drugs

Description

ChEBI: A member of the class of piperazines in which the two amino hydrogens of piperazine are replaced by 2-benzoylpropyl and 2-ethoxy-2-phenylethyl groups.


Eprazinone is a member of the class of piperazines in which the two amino hydrogens of piperazine are replaced by 2-benzoylpropyl and 2-ethoxy-2-phenylethyl groups. It has a role as a mucolytic. It is a N-alkylpiperazine, an ether and an aromatic ketone. It is a conjugate base of an eprazinone(2+).|Eprazinone (trade name Eftapan) is a mucolytic drug, and relieves bronchospasms.

Eprazinone Basic Attributes

380.52

380.52

233-873-3

883YNL63WU

DTXSID1048336

R - Respiratory system

2933599090

Characteristics

32.8

3.58

1.0909 (rough estimate)

160

508.13°C (rough estimate)

258.5±30.1 °C

1.5500 (estimate)

Drug Information

Agents that increase mucous excretion. Mucolytic agents, that is drugs that liquefy mucous secretions, are also included here. (See all compounds classified as Expectorants.)

1-(2-phenyl-2-ethoxy)ethyl-4-(2-benzyloxy)propylpiperazine

Eprazinone Use and Manufacturing

Antitussive, used for acute and chronic bronchitis, pneumonia, tuberculosis and other diseases, especially for antitussive and expectorant for chronic bronchitis

Computed Properties

Molecular Weight:380.5
XLogP3:3.7
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:380.246378268
Monoisotopic Mass:380.246378268
Topological Polar Surface Area:32.8
Heavy Atom Count:28
Complexity:450
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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