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Palmatine chloride

Palmatine chloride structure

CAS No:
10605-02-4
Formula:
C21H22ClNO4
Chemical Name:
Palmatine chloride
Synonyms:
2,3,9,10-TETRAMETHOXYPROTOBERBERINCHLORIDE;BERBERICINE CHLORIDE;PALMATINE CHLORIDE;PALMATINE HYDROCHLORIDE;Palmatine HCL;2,3,9,10-Tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium chloride;PalMatin hydrochloride;Palmatine chloride 2,3,9,10-Tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium chloride
Categories:
Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs

Description

Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties. IC50 value:Target:In vitro: Experimental set examined the influence of palmatine on osteoblast-like cells in vitro. In the culture supernatant of MC3T3-E1 cells, RANKL and OPG levels were significantly reduced by palmatine addition [1]. In vivo: The first experimentaI set was designed to histologically and biochemically examine mice randomly divide

Palmatine chloride Basic Attributes

Molecular Weight：

387.86

Exact Mass：

387.123749

UNII：

ZJ6W8881Z8

NSC Number：

209407

HScode：

29339900

Characteristics

PSA：

40.8

XLogP3：

0.38880

Melting Point：

205℃

Refractive Index：

1.624

Vapor Pressure：

6.6E-15mmHg at 25°C

Collision Cross Section：

185.6 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Safety Information

hazard class code：

20/22-36/38

safety instructions：

24/45

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 2 companies from 1 notifications to the ECHA C&L Inventory.

Drug Information

MeSH Entry Terms：

berbericinine

Palmatine chloride Use and Manufacturing

antibacterial, antimalarial, uterine contractant

Computed Properties

Molecular Weight:387.9
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:387.1237359
Monoisotopic Mass:387.1237359
Topological Polar Surface Area:40.8
Heavy Atom Count:27
Complexity:475
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Related Drugs

Fructus lutein vaginal gel
Ingredients	The main ingredients are flavonoids (palmitine hydrochloride, palmatine hydrochloride, palmatine hydrochloride).
Indication	If used with other drugs, drug interactions may occur. Please consult your doctor or pharmacist for details.
Specifications	5g:50mg

Fructus lutein vaginal gel
Ingredients	The main ingredients are flavonoids (palmitine hydrochloride, palmatine hydrochloride, palmatine hydrochloride).
Indication	If used with other drugs, drug interactions may occur. Please consult your doctor or pharmacist for details.
Specifications	5g:50mg

Recommended Suppliers of Palmatine chloride

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Palmatine hydrochloride, CAS:10605-02-4

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CAS No.: 10605-02-4

Grade: Chemical Grade

Content: 99%

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Palmatine chloride

CAS No.: 10605-02-4

Grade: Industrial Grade

Content: 98%

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