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Phleomycin

Phleomycin structure

CAS No:
11006-33-0
Chemical Name:
Phleomycin
Synonyms:
Phleomycin
Categories:
Biochemical Engineering > Saccharides

Description

Water-soluble, copper-containing low molecular weight polypeptides obtained from the culture medium of Streptomyces verticillus. They are specific inhibitors of DNA synthesis in bacteria and have been found to act as antitumor agents. They have also been used against rust fungi of plants.

Phleomycin Basic Attributes

Molecular Weight：

1326.379

Exact Mass：

1323.47000

UNII：

BN3E7WJN9X

DSSTox ID：

DTXSID0031893

HScode：

29419059

Characteristics

PSA：

702

XLogP3：

-10.2

Appearance：

light blue

Density：

1.3193 (rough estimate)

Boiling Point：

527.46°C (rough estimate)

Flash Point：

993.3ºC

Refractive Index：

1.5600 (estimate)

Water Solubility：

H2O: 10 mg/mL, clear, blue

Storage Conditions：

2-8°C

Safety Information

Packing level：

III

Hazard category：

6.1(b)

Transport codes：

2811

wgk germany：

hazard class code：

22-36/37/38

safety instructions：

26-36

RTECS Number：

SY0525000

Marks：

Xn,Xi

Precautionary statement(s)：

P264, P270, P301+P312, P330, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory.

Drug Information

MeSH：

Chemical substances, produced by microorganisms, inhibiting or preventing the proliferation of neoplasms. (See all compounds classified as Antibiotics, Antineoplastic.)|Compounds that inhibit cell production of DNA or RNA. (See all compounds classified as Nucleic Acid Synthesis Inhibitors.)

MeSH Entry Terms：

Phleomycin

Computed Properties

Molecular Weight:1326.4
XLogP3:-10.2
Hydrogen Bond Donor Count:20
Hydrogen Bond Acceptor Count:31
Rotatable Bond Count:31
Exact Mass:1325.47648482
Monoisotopic Mass:1325.47648482
Topological Polar Surface Area:702
Heavy Atom Count:91
Complexity:2650
Defined Atom Stereocenter Count:9
Undefined Atom Stereocenter Count:10
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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CAS No.: 11006-33-0

Grade: Pharmaceutical Grade

Content: 98%

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Guide of Phleomycin

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Computed Properties
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Phleomycin

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