Rocuronium bromide
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Rocuronium bromide
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CAS No:
119302-91-9
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Formula:
C32H53N2O4.Br
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Chemical Name:
Rocuronium bromide
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Synonyms:
Pyrrolidinium,1-[(2β,3α,5α,16β,17β)-17-(acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)-,bromide;Androstane,pyrrolidinium deriv.;Org 9426;Rocuronium bromide;Zemuron;Esmeron;(+)-Rocuronium bromide
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CAS No:
Description
Crystallization; melting temperature of 161~169 °C. [α] D20 + 18.7 ° (C = 1.03, chloroform). Off-white SolidChEBI: The organic bromide salt of a 5alpha androstane compound having 3alpha-hydroxy-, 17beta-acetoxy-, 2beta-morpholino- and 16beta-N-allyllyrrolidinium subsituents.Rocuronium bromide is a short-acting nondepolarizing steroidal neuromuscularblocker introduced in the U.S.A as Zemuron and in the United Kingdom as Esmeron.k is indicated for use as an adjunct to general anesthesia
Characteristics
59.00000
1.30820
Solid
161-169 °C
H2O: soluble100mg/mL, clear, light yellow
room temp
D20 +18.7° (c = 1.03 in CHCl3)
Rocuronium bromide Use and Manufacturing
A non-depolarizing neuromuscular blocker used in anesthesia to help insert breathing tubes. Muscle relaxants. Non-depolarizing neuromuscular blocker. It is used for general anesthesia and conventional tracheal intubation for inpatients and outpatients. It can relax the skeletal muscles during surgery and mechanical ventilation.
Drug Function and Efficacy
Muscle relaxants, used to relax skeletal muscles during general anesthesia
Registered Holders
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CURIA Italy SRL
Active
United States
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Farmhispania S.A.
Active
Japan
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Aspen Oss B.V.
Active
Netherlands
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