iodine
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iodine
structure -
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CAS No:
12190-71-5
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Formula:
I2
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Chemical Name:
iodine
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Synonyms:
Iodine;Iodide (I21-) (8CI,9CI);Iodine test solution(ChP);Iodine Crystals or Liquid;iodien;Iodine solution standard substance;Iodine test solution;TIANFU-CHEM Iodine
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Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System
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CAS No:
Description
Violet solid with a sharp, characteristic odor.
Iodine,I, is a nonmetallic element with an orthorhombic crystal structure, a violet to black color. This poisonous element sublimes readily and is easily purified in this manner. It is insoluble in water,but is soluble in common solvents such as alcohol, ether,and carbon tetrachloride. Iodine is used as a germicide, an antiseptic, in dyes,tinctures, and pharmaceuticals. It is also used in the production of vanadium metal in the McKechnie-Seybolt process, which is the reduction of vanadium pentoxide in the presence of iodine. Iodine is used in a similar manner in the production of high-purity zirconium.For many years, iodine tincture(3% to 7% dissolved in ethyl alcohol) has been an important antiseptic. The commercial tinctures also usually contain 5% potassium iodide to provide stability. This form produces a mild burning of the skin and stains both skin and fabrics. A milder preparation is available in which about 2% iodine is contained in an oil-water emulsion which also contains lecithin.
Heavy, grayish-black plates or granules having a metallic luster; characteristic odor. Readily sublimed having a violet vapor.Soluble in alcohol, carbon disulfide, chloroform, ether, carbon tetrachloride, glycerol, and alkaline iodide solutions; insoluble
Iodine was first discovered by Barnard Courtois, a French chemist in 1811 while extracting potassium and sodium from seaweed ash. When he accidentally added sulfuric acid, a violet colored cloud evolved from the mass. The resulting gas was condensed into dark crystals-the first occurrence of observed solid iodine.Courtois analyzed them and then gave some of them to a fellow chemist, Joseph Louis Gay-Lussac, for further study.Two years later, Gay-Lussac presented his study to the scientific community, announcing the discovery of a new element that he named "iodine," after the Greek word "ioeides" meaning violet colored.A Swiss physician by the name of J.F. Coindet had previously used burnt sponge and seaweed for the treatment of goiter (an enlargement of the thyroid gland). This treatment had been in use since 3600 B.C., when it appeared in Chinese medical writings, as well as writings by the Greek physician Hippocrates. Upon hearing of the work of Courtois and Gay-Lussac, Coindet suspected that iodine might be the active ingredient in seaweed that cured goiter. In 1819, he successfully tested a tincture of iodine on 150 patients, significantly reducing the size of their goiter within one week. As a result of these early studies, in the 1830s the medical community started advocating for iodine supplements to decrease the occurrence of goiter.
A dark-violet volatile solid element belonging to the halogens (group 17 of the periodic table). It occurs in seawater and is concentrated by various marine organisms in the form of iodides. Significant deposits also occur in the form of iodates. The element is conveniently prepared by the oxidation of iodides in acid solution (using MnO2). Industrial methods similarly use oxidation of iodides or reduction of iodates to iodides by sulfur(IV) oxide (sulfur dioxide) followed by oxidation, depending on the source of the raw materials. Iodine and its compounds are used in chemical synthesis, photography, pharmaceuticals, and dyestuffs manufacture.Iodine has the lowest electronegativity of the stable halogens and consequently is the least reactive. It combines only slowly with hydrogen to form hydroiodic acid, HI. Iodine also combines directly with many electropositive elements, but does so much more slowly than does bromine or chlorine. Because of the larger size of the iodine ion and the consequent low lattice energies, the iodides are generally more soluble than related bromides or chlorides. As with the other halides, iodides of Ag(I), Cu(I), Hg(I), and Pb(II) are insoluble unless complexing ions are present.Iodine also forms a range of covalent iodides with the metalloids and non-metallic elements (this includes a vast range of organic iodides) but these are generally less thermodynamically stable and are more readily hydrolyzed than chlorine or bromine analogs.
Characteristics
0
Iodine in its pure state is a black solid that sublimates (changes from a solid to a gas withoutgoing through a liquid state) at room temperature. It produces a deep purple vapor that is irritatingto the eyes, nose, and throat. Iodine tends to form nonmetallic diatomic molecules (I2).It is the heaviest of the naturally occurring halogens. (Although astatine, the fifth element ingroup 17, is heavier than iodine, it is a synthetic element and does not occur in nature exceptas a very small trace.) Iodine is the least reactive of the five halogens.Iodine’s melting point is 113.7°C, its boiling point is 184.4°C, and its density is 4.93g/cm3.
2.49
Violet-black crystals with a metallic luster and a sharp odor. Mp: 133.5°C, bp: 185°C. Emits toxic vapor at room conditions; vapor becomes visibly purple when its concentration builds up in a confined space. Nearly insoluble in water but very soluble in aqueous solutions of iodides.
4.93
236°F
365°F
1.788
0.01%
Materials which are toxic as stored or which can decompose into toxic components Should be stored in a cool, well-ventilated place, out of the direct rays of the sun, away from areas of high fire hazard, and should be periodically inspected. Incompatible materials should be isolated .
Vapour pressure, kPa at 25°C: 0.04
Relative vapour density (air = 1): 8.8
Noncombustible Solid
Sharp characteristic odor.
Sharp, acrid
Safety Information
III
8
3085
20/21-50
(2)-23-25-61
NN1575000
Xn, N
Separated from incompatible materials. See Chemical Dangers. Well closed. Ventilation along the floor.
Readily sublimes at room temperature, forming violet corrosive vapor.
P261, P271, P273, P280, P302+P352, P304+P312, P304+P340, P312, P322, P363, P391, P501
less than pure form, it can damage the skin, eyes, and mucous membranes. Both the elementalform and its compounds (gases, liquids, or solids) are toxic if inhaled or ingested. Even indiluted form (e.g., a tincture of iodine to treat minor skin wounds), it should be used withcare.Although a poison in high concentrations, iodine is required as a trace element in our dietsto prevent thyroid problems and mental retardation in the very young.
UN 3495
iodine Use and Manufacturing
Mainly used in the manufacture of iodide, used in the manufacture of pesticides, feed additives, dyes, iodine, test paper, drugs, etc. used to prepare equivalent solvents, determine the iodine value, calibrate the concentration of sodium thiosulfate solution, the solution can be used as a disinfectant, photographic plate Used in the preparation of iodine and thinner
Dyes (aniline dyes, phthalein dyes), alkylation and condensation catalyst, iodides, iodates, antiseptics and germicides, X-ray contrast media, food and feed additive, stabilizers, photographic film, water treatment, pharmaceuticals, medicinal soaps, unsat
Iodine is a halogen element extracted from chilean nitrate-bearing earth or from seaweed. it functions by its presence in the thyroid hormones. iodine deficiency is associated with goiter. sources are potassium and cuprous iodide and potassium and calcium iodate, of which the iodate form is preferred because of better stability. it is used as a food supplement.
One of the most important uses of iodine is in the treatment of hypothyroidism, a conditionin which the thyroid gland is deficient in iodine. Iodine deficiency may lead to the formationof a goiter, wherein the gland that surrounds the windpipe in the neck becomes enlarged.There are other causes of goiter, including cancer of the thyroid gland. A deficiency of iodinecan also cause cretinism (infant hypothyroidism) in newborn babies, which can result inmental retardation unless the subject takes thyroid hormones for a lifetime. Green leafy foods,among other foods, contain iodine that when taken into the human body ends up in thethyroid gland. Some food grown in iodine-deficient soils do not contain adequate iodine forour diets. This is why iodine was added to table salt (about 0.01% potassium iodide) decadesago, specifically for people who live in regions with iodine-poor soils. The area around theGreat Lakes in the United States is one region with soil that is deficient in iodine. A healthydiet requires 90 to 150 micrograms of iodine each day that, in addition to being available iniodized salt, can be obtained from eating a balanced diet, including seafood.The isotope iodine-131 is an artificial radioisotope of iodine used as a tracer in biomedicalresearch and as a treatment for thyroid disease. I-131 has a half-life of about eight days, whichmeans it will be eliminated from the body in several weeks.In industry, iodine is used for dyes, antiseptics, germicides, X-ray contrast medium, foodand feed additives, pharmaceuticals, medical soaps, and photographic film emulsions and as alaboratory catalyst to either speed up or slow down chemical reactions.Iodine is also used as a test for starch. When placed on starch (a potato for example), iodineturns the starch a dark blue color. Silver iodide is used in the manufacture of photographicfilm and paper. It is also used to “seed” clouds because of its ability to form a large numberof crystals that act as nuclei upon which moisture in the clouds condenses, forming raindropsthat may result in rain.
Drug Function and Efficacy
This product is a disinfectant and preservative. Its mechanism of action is to denature and kill bacterial proteins. It has a killing effect on bacteria, fungi, and viruses.
Registered Holders
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Shandong Jiejing Group Corporation
Active
China
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Zigong Honghe Pharmacy Co., Ltd.
Active
China
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Sichuan Jianneng Pharmaceutical Co., Ltd.
Active
China
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