 Home > Encyclopedia > MTS Reagent

MTS Reagent

MTS Reagent structure

CAS No:
138169-43-4
Formula:
C20H17N5O6S2
Chemical Name:
MTS Reagent
Synonyms:
5-[3-(Aarboxymethoxy)phenyl]-3-(4,5-dimethyl-2-thiazolyl)-2-(4-sulfophenyl)-2H-tetrazolium inner salt;2H-TetrazoliuM,5-[3-(carboxyMethoxy)phenyl]-3-(4,5-diMethyl-2-thiazolyl)-2-(4-sulfophenyl)-,inner salt;5-[3-(Carboxymethoxy)phenyl]-3-(4,5-dimethyl-2-thiazolyl)-2-(4-sulfophenyl)-2H-tetrazolium inner salt;4-{5-[3-(Carboxymethoxy)phenyl]-3-(4,5-dimethyl-1,3-thiazol-2-yl)-2H-tetrazol-3-ium-2-yl}benzenesulfonate;METOLOSE(R);'TYLOSE'(R) MH 1000;'TYLOSE'(R) MH 300;MTS(dye)
Categories:
Active Pharmaceutical Ingredients > Specialty Drugs

Description

MTS reagent is one of the most common water-soluble tetrazolium reagents that are widely used to quantify cell viability by absorption spectrophotometry. A variety of tetrazolium inner salts are used for determining cell viability in proliferation assays by monitoring their color changes. Metabolically active cells reduce colorless tetrazolium inner salts into the colored formazan products that might be either soluble or insoluble in cell culture media depending on the structures of tetrazolium reagents. The conversion of tetrazolium inner salts to formazans is thought to be carried out by NAD(P)H-dependent dehydrogenase enzymes.

MTS Reagent Basic Attributes

Molecular Weight：

487.515

Exact Mass：

487.062012

EC Number：

232-674-9

DSSTox ID：

DTXSID20160514

HScode：

3912900000

Characteristics

PSA：

187.83000

XLogP3：

2.73260

Appearance：

powder

Safety Information

wgk germany：

safety instructions：

24/25

RTECS Number：

FJ5959000

Drug Information

MeSH Entry Terms：

3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium

Computed Properties

Molecular Weight:487.5
XLogP3:4.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:6
Exact Mass:487.06202563
Monoisotopic Mass:487.06202563
Topological Polar Surface Area:188
Heavy Atom Count:33
Complexity:777
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes