Landiolol hydrochloride
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Landiolol hydrochloride
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CAS No:
144481-98-1
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Formula:
C25H39N3O8.ClH
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Chemical Name:
Landiolol hydrochloride
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Synonyms:
Benzenepropanoic acid,4-[(2S)-2-hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]-,[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl ester,hydrochloride (1:1);Benzenepropanoic acid,4-[2-hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]-,(2,2-dimethyl-1,3-dioxolan-4-yl)methyl ester,monohydrochloride,[S-(R*,R*)]-;Benzenepropanoic acid,4-[(2S)-2-hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]-,[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl ester,monohydrochloride;ONO 1101 hydrochloride;Landiolol hydrochloride;Onoact;Corebeta;Rapibloc;2097506-26-6
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Categories:
Active Pharmaceutical Ingredients > Circulatory System Drugs
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CAS No:
Description
Landiolol hydrochloride (ONO1101 hydrochloride) is a highly beta1 selective ultra-short acting beta-blocker (β1/β2 selectivity = 255:1, a half-life of 4 min)， acts as an adrenoceptor antagonist[1].
Characteristics
127.82000
2.37760
White crystalline powder
1.201g/cm3
125.4°
727.5ºC at 760mmHg
393.8ºC
3.24E-22mmHg at 25°C
LD50 in mice (mg/kg): 290 i.v. (Iguchi)
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