 Home > Encyclopedia > Nomegestrol acetate

Nomegestrol acetate

Nomegestrol acetate structure

CAS No:
58652-20-3
Formula:
C23H30O4
Chemical Name:
Nomegestrol acetate
Synonyms:
19-Norpregna-4,6-diene-3,20-dione,17-(acetyloxy)-6-methyl-;17-(Acetyloxy)-6-methyl-19-norpregna-4,6-diene-3,20-dione;6-Methyl-17α-acetoxy-Δ6-19-norprogesterone;TX 066;Nomegestrol acetate;Lutenyl;Uniplant;Surplant;Org 10486-0
Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Description

Nomegestrol acetate is a potent, highly selective progestogen, which is characterized as a full agonist at the progesterone receptor, with no or minimal binding to other steroid receptors, including the androgen and glucocorticoid receptors[1].

Nomegestrol acetate is a corticosteroid hormone.|Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.

Nomegestrol acetate Basic Attributes

Molecular Weight：

370.48

Exact Mass：

370.48

EC Number：

261-379-8

UNII：

83J78V5W05

DSSTox ID：

DTXSID90207349

ATC Code：

G03AA14

Characteristics

PSA：

60.4

XLogP3：

3.34

Appearance：

white to tan

Density：

1.2±0.1 g/cm3

Boiling Point：

507.3±50.0 °C at 760 mmHg

Flash Point：

219.8±30.2 °C

Refractive Index：

1.554

Water Solubility：

DMSO: ≥7mg/mL

Storage Conditions：

2-8°C

Safety Information

Transport codes：

UN 3077 9 / PGIII

wgk germany：

hazard class code：

63-50

safety instructions：

RTECS Number：

RC8899200

Marks：

Precautionary statement(s)：

P280

Hazard Statements：

H361fd-H400

GHS Classification：

|Danger|H360 (32.26%): May damage fertility or the unborn child [Danger Reproductive toxicity]|P201, P202, P273, P281, P308+P313, P391, P405, and P501|Aggregated GHS information provided by 64 companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Drug Indication：

Oral contraception|Oral contraception.|Contraception

MeSH Entry Terms：

nomegestrol acetate

Nomegestrol acetate Use and Manufacturing

Uses

Contraceptive

Use Classification：

Human drugs -> Zoely -> EMA Drug Category|Sex hormones and modulators of the genital system -> Human pharmacotherapeutic group|Human drugs -> Ioa -> EMA Drug Category|Human Drugs -> EU pediatric investigation plans

Computed Properties

Molecular Weight:370.5
XLogP3:2.6
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:370.21440943
Monoisotopic Mass:370.21440943
Topological Polar Surface Area:60.4
Heavy Atom Count:27
Complexity:775
Defined Atom Stereocenter Count:6
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Nomegestrol acetate

SHANDONG LOOK CHEMICAL CO.,LTD Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate,Pigment & Dyestuff,Polymer,Flavour & Fragrance,Basic Organic Chemicals,Pharmaceutical

Nomegestrol Acetate in stock

CAS No.: 58652-20-3

Inquiry
Xiamen Eagle Chemical Corporation Contact Supplier

CN
2 YRS

Business licensed

Trader Supplier of Dimethyl sufoxide

58652-20-3 Nomegestrol Acetate

CAS No.: 58652-20-3

Grade: Industrial Grade

Content: 99.5%

Inquiry