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Nomegestrol

Nomegestrol structure

CAS No:
58691-88-6
Formula:
C21H28O3
Chemical Name:
Nomegestrol
Synonyms:
19-Norpregna-4,6-diene-3,20-dione,17-hydroxy-6-methyl-;17-Hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione;Nomegestrol;TX 071;Monaco;Thermex
Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Description

Nomegestrol is a potent and orally available progestin, acts as a selective full progesterone receptor agonist, with a Kd of 5.44 nM for rat uterine progesterone receptor, and has moderate antiandrogenic activity and strong antiestrogenic activity.

Nomegestrol is a corticosteroid hormone.|Nomegestrol is an ingredient in the EMA-authorised product Zoely.

Nomegestrol Basic Attributes

Molecular Weight：

328.45

Exact Mass：

328.45

UNII：

10F89177CO

ATC Code：

G - Genito urinary system and sex hormones

Characteristics

PSA：

54.4

XLogP3：

2.58

Density：

1.2±0.1 g/cm3

Melting Point：

204-205ºC

Boiling Point：

502.6±50.0 °C at 760 mmHg

Flash Point：

271.8±26.6 °C

Refractive Index：

1.574

Drug Information

MeSH Entry Terms：

Lutenyl

Nomegestrol Use and Manufacturing

Progetin used in implantable hormone replacement therapies.

Computed Properties

Molecular Weight:328.4
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:328.20384475
Monoisotopic Mass:328.20384475
Topological Polar Surface Area:54.4
Heavy Atom Count:24
Complexity:673
Defined Atom Stereocenter Count:6
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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CAS No.: 58691-88-6

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