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Lisinopril

Lisinopril structure

CAS No:
76547-98-3
Formula:
C21H31N3O5
Chemical Name:
Lisinopril
Synonyms:
L-Proline,N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-;L-Proline,1-[N2-(1-carboxy-3-phenylpropyl)-L-lysyl]-,(S)-;N2-[(1S)-1-Carboxy-3-phenylpropyl]-L-lysyl-L-proline;MK 521;N-(1(S)-Carboxy-3-phenylpropyl)-L-lysyl-L-proline;Lisinopril;MK 522;Zestril;Prinivil;N2-[(S)-1-Carboxy-3-phenylpropyl]-L-lysyl-L-proline;Carace;Cipral;Cipril;Coric;Inopril;Acerbon;Alapril;Lipril;Lisipril;Lisoril;Lispril;Listril;Noperten;Novatec;Presiten;Prinil;Prinvil;Tensopril;Tensyn;Vivatec;Linopril;Linvas;Lisopril;Lizonoton;Nanopril;Diroton;Longes;Lisitec;Loril;Skopryl;Amicor;Irumed;Laaven;Lizinopril;Optimon;Vitopril;Lisigamma;Lisinopril Sandoz;Ranolip
Categories:
Active Pharmaceutical Ingredients > Circulatory System Drugs

Description

Lisinopril is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.Target: ACELisinopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Lisinopril may be used to treat hypertension and symptomatic cong

Lisinopril Basic Attributes

Molecular Weight：

405.49

Exact Mass：

405.49

EC Number：

278-488-1

HScode：

2933990090

Characteristics

PSA：

133

XLogP3：

-2.9

Appearance：

white solid

Density：

1.3±0.1 g/cm3

Melting Point：

162-165 °C

Boiling Point：

666.4°C at 760 mmHg

Flash Point：

356.9±31.5 °C

Refractive Index：

1.578

Water Solubility：

97 mg/mL

Storage Conditions：

2-8°C

Vapor Pressure：

3.95X10-15 mm Hg at 25 deg C (est)

PKA：

2.5(at 25 °C)

Safety Information

wgk germany：

safety instructions：

22-24/25

RTECS Number：

TW3589990

Stability/Shelf Life：

Stable under recommended storage conditions.

Precautionary statement(s)：

P201, P202, P260, P264, P280, P281, P305+P351+P338, P308+P313, P314, P337+P313, P405, P501

Hazard Statements：

H319

Lisinopril Use and Manufacturing

Labeled Lisinopril, intended for use as an internal standard for the quantification fo Lisinopril by GC- or LC-mass spectrometry.

Material

Trifluoroacetic acid

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