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Imidapril hydrochloride

Imidapril hydrochloride structure

CAS No:
89396-94-1
Formula:
C20H27N3O6.ClH
Chemical Name:
Imidapril hydrochloride
Synonyms:
4-Imidazolidinecarboxylic acid,3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-,hydrochloride (1:1),(4S)-;4-Imidazolidinecarboxylic acid,3-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-,monohydrochloride,[4S-[3[R*(R*)],4R*]]-;4-Imidazolidinecarboxylic acid,3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-,monohydrochloride,(4S)-;Imidapril hydrochloride;TA 6366;Tanapril;Novaloc;Tanatril
Categories:
Active Pharmaceutical Ingredients > Circulatory System Drugs

Description

Imidapril Hydrochloride is the hydrochloride salt of Imidapril, an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Target: ACEAs a prodrug, Imidapril is converted by hydrolysis in the liver into its active form imidaprilat. Imidaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Imidaprilat also dec

Imidapril hydrochloride Basic Attributes

Molecular Weight：

405.44488

Exact Mass：

441.167

EC Number：

1308068-626-2

Characteristics

PSA：

116

XLogP3：

1.14290

Appearance：

white to tan

Melting Point：

214-216 °C (decomp)

Boiling Point：

577ºC at 760 mmHg

Water Solubility：

H2O: ≥5mg/mL

Storage Conditions：

-20°C

Specific rotation：

D20 -64.1° (c = 0.5 in ethanol)

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

RTECS Number：

NI8927400

Precautionary statement(s)：

P201, P202, P261, P264, P271, P280, P281, P302+P352, P304+P340, P305+P351+P338, P308+P313, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

Hazard Statements：

H315

Imidapril hydrochloride Use and Manufacturing

antibiotic

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Imidapril hydrochloride

CAS No.: 89396-94-1

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CAS No.: 89396-94-1

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