Paris VII
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Paris VII
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CAS No:
68124-04-9
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Formula:
C51H82O21
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Chemical Name:
Paris VII
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Synonyms:
β-D-Glucopyranoside,(3β,25R)-17-hydroxyspirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[O-6-deoxy-α-L-mannopyranosyl-(1→4)-6-deoxy-α-L-mannopyranosyl-(1→4)]-;Spirostan,β-D-glucopyranoside deriv.;Spiro[8H-naphth[2′,1′:4,5]indeno[2,1-b]furan-8,2′-[2H]pyran],β-D-glucopyranoside deriv.;(3β,25R)-17-Hydroxyspirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[O-6-deoxy-α-L-mannopyranosyl-(1→4)-6-deoxy-α-L-mannopyranosyl-(1→4)]-β-D-glucopyranoside;Pennogenin 3-O-rhamnosylchacotrioside;Pennogenin 3-O-α-L-rhamnopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside;Dioscinin;Paris VII;Saponin Tg;Pennogenin 3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranoside;Chonglouoside VII;17-Hydroxyparis II;Paris saponin VII;(25R)-17α-Hydroxyspirost-5-en-3β-yl O-α-L-rhamnopyranosyl-(1→2)-O-[O-α-L-rhamnopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranoside;Pennogenin-3-O-α-L-rhamnopyranosyl-(1→4)-O-α-L-rhamnopyranosyl-(1→4)-O-[α-L-rhamnopyranosyl-(1→2)]-O-β-D-glucopyranoside;Pennogenin-3-O-α-L-rhamnopyranosyl(1→4)-α-L-rhamnopyranosyl(1→4)-[α-L-rhamnopyranosyl(1→2)]-β-D-glucoside;11048-77-4;55916-45-5;1427449-46-4
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CAS No:
Description
Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii Maxim. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with Akt/MAPK and the inhibition of P-gp. Paris saponin VII attenuates mitochondrial membrane potential, increases the expression of apoptosis-related proteins, such as Bax and cytochrome c, and decreases the protein expression levels of Bcl-2, caspase-9, caspase-3, PARP-1, and p-Akt. Paris
Computed Properties
Molecular Weight:1031.2
XLogP3:-1
Hydrogen Bond Donor Count:11
Hydrogen Bond Acceptor Count:21
Rotatable Bond Count:9
Exact Mass:1030.53485962
Monoisotopic Mass:1030.53485962
Topological Polar Surface Area:315
Heavy Atom Count:72
Complexity:1950
Defined Atom Stereocenter Count:31
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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