Helicid
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Helicid
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CAS No:
80154-34-3
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Formula:
C13H16O7
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Chemical Name:
Helicid
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Synonyms:
helicid;helicide;4-formylphenyl hexopyranoside;C13H16O7;Helicide;Hilicidum;ChemDiv1_020960;HMS646I16;4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzaldehyde;4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzaldehyde
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CAS No:
Description
Helicid (Helicide, Helicidum, 4-Formylphenyl-β-D-allopyranoside) is a major constituent of Helicia nilgirica Bedd. Helicid has been used to treat psychoneurosis for its sedative-hypnotic and analgesic properties[1].
Characteristics
116
-1.32220
White to Off-white Powder
1.5±0.1 g/cm3
199-200°C
559.9°C at 760 mmHg
215.8±23.6 °C
1.651
soluble in hot water. Slightly soluble in water, ethanol or carbinol. Insoluble in aether or chloroform.
-27 º (c=3.2, MeOH)
Computed Properties
Molecular Weight:284.26
XLogP3:-0.9
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:284.08960285
Monoisotopic Mass:284.08960285
Topological Polar Surface Area:116
Heavy Atom Count:20
Complexity:316
Defined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
It can restore the imbalance between the excitation and inhibition processes of the cerebral cortex, and has central inhibitory effects such as sedation, hypnosis and analgesia
Registered Holders
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Yunnan Yuxi Wanfang NATURAL MEDICINE Co., Ltd.
Active
China
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Chuxiong Yunzhi Phytopharmaceutical Co., Ltd.
Active
China
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Yunnan Baiyao Group Dali Pharmaceutical Co., Ltd.
Active
China
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