Product
Supplier
Encyclopedia
Inquiry

EN

Home > Encyclopedia > GW-501516

GW-501516

GW-501516 structure
  • CAS No:

    317318-70-0

  • Formula:

    C21H18F3NO3S2

  • Synonyms:

    endurobol;GW 1516;GW 501516;GW-1516;GW-501516;GW1516;GW501516

  • Categories:

    API  >  Inhibitor Drugs

Request for Quotation

Description

GW 501516 is a PPARδ agonist with an EC50 of 1.1 nM.

View AllView Less

Basic Attributes

  • 317318-70-0

  • C21H18F3NO3S2

  • 453.5

  • 453.068024

  • 112.96000

  • 6.29

  • 1592732-453-0

  • YDBLKRPLXZNVNB-UHFFFAOYSA-N

  • 9

  • 1

  • 7

Characteristics

  • white to beige

  • 1.4±0.1 g/cm3

  • 134-136°C

  • 584.5±60.0 °C at 760 mmHg

  • 307.3±32.9 °C

  • 1.619

  • DMSO: soluble20mg/mL, clear

  • Refrigerator

  • Light Sensitive

Safety Information

  • NONH for all modes of transport

  • 3

  • AI9105500

Usage

An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream.A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells.

View AllView Less

Scan the QR Code to Share

Suggestions
Email:
Message:
Send Message