Isoconazole nitrate
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Isoconazole nitrate
structure -
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CAS No:
24168-96-5
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Formula:
C18H14Cl4N2O.HNO3
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Chemical Name:
Isoconazole nitrate
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Synonyms:
1H-Imidazole,1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-,nitrate (1:1);Imidazole,1-[2,4-dichloro-β-[(2,6-dichlorobenzyl)oxy]phenethyl]-,mononitrate;1H-Imidazole,1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-,mononitrate;Isoconazole nitrate;Adestan G 100;Gyno-Travogen;Fazol;Travogen;R 15454;Travogyn
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CAS No:
Description
Isoconazole nitrate is a broad-spectrum antimicrobial agent with a highly effective antimycotic and gram-positive antibacterial activity, a rapid rate of absorption and low systemic exposure potential. Isoconazole nitrate is effective against pathogens involved in dermatomycoses, with minimum inhibitory concentrations well below the concentration of ISN in skin and hair follicles.
Characteristics
93.1
6.63030
White crystals or crystalline powder
1.4 g/cm3
182-183 °C
555.1ºC at 760 mmHg
289.5ºC
Refrigerator
Safety Information
NI4772000
P273, P391, P501
H400
|Warning|H400 (94.44%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]|P273, P391, and P501|Aggregated GHS information provided by 37 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. (See all compounds classified as Antifungal Agents.)
1-(2,4-dichloro beta-(2,6-dichlorobenzyloxy)phenethyl) imidazole
Computed Properties
Molecular Weight:479.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:478.978717
Monoisotopic Mass:476.981667
Topological Polar Surface Area:93.1
Heavy Atom Count:29
Complexity:431
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Antifungal effect
Registered Holders
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ERREGIERRE SPA
Active
Italy
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Sichuan Baili Pharmaceutical Co., Ltd.
Inactive
China
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JANSSEN PHARMACEUTICA NV
Inactive
European Union
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