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Apramycin

Apramycin structure

Apramycin 

structure
  • CAS No:

    37321-09-8

  • Formula:

    C21H41N5O11

  • Chemical Name:

    Apramycin

  • Synonyms:

    D-Streptamine,O-4-amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-;Pyrano[3,2-b]pyran,D-streptamine deriv.;O-4-Amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-D-streptamine;Nebramycin II;Apramycin;Ambylan;EL 857;Nebramycin factor 2;Apralan;Apralan 200 Injection;Apralan Soluble;Apralan solubile;Apralin;EL 857/820;37304-82-8;41194-16-5

  • Categories:

    Active Pharmaceutical Ingredients  >  Antibiotics

Description

Apramycin(Nebramycin II) is an aminoglycoside antibiotic used in veterinary medicine. IC50 value:Target: Apramycin stands out among aminoglycosides for its mechanism of action which is based on blocking translocation and its ability to bind also to the eukaryotic decoding site despite differences in key residues required for apramycin recognition by the bacterial target. The drug binds in the deep groove of the RNA which forms a continuously stacked helix comprising non-canonical C.A and

Apramycin Basic Attributes

539.58

539.58

253-460-1

Characteristics

284

-7

1.56 g/cm3

823ºC at 760 mmHg

451.6ºC

1.657

Safety Information

P264, P273, P280, P302+P352, P321, P332+P313, P362, P391, P501

H315

Apramycin Use and Manufacturing

Antibacterial.

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