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Cefcapene pivoxil hydrochloride monohydrate

Cefcapene pivoxil hydrochloride monohydrate structure

CAS No:
147816-24-8
Formula:
C23H32ClN5O9S2
Chemical Name:
Cefcapene pivoxil hydrochloride monohydrate
Synonyms:
2,2-dimethylpropanoyloxymethyl 7-[2-(2-amino-1,3-thiazol-4-yl)pent-2-enoylamino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;CEFCAPENE PIVOXIL HCL;Cefcapene pivoxil hydrochloride;5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)-7-((2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl)amino)-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester,(6R-(6-alpha,7-beta(Z)))-, monohydrochloride, hydrate;Cefcapene Pivoxil Hydrochloride Monohydrate;(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, (2,2-Dimethyl-1-oxopropoxy)methyl Ester Hydrochloride;Flomox;Cefcapene pivoxil hydrochloride hydrate
Categories:
Active Pharmaceutical Ingredients > Antibiotics

Description

Off-White Solid

Cefcapene Pivoxil Hydrochloride Hydrate is the hydrate hydrochloride salt form of cefcapene pivalate, a prodrug and third-generation cephalosporin with antibacterial activity. After oral administration of cefcapene pivoxil hydrochloride hydrate the ester bond is cleaved, releasing active cefcapene.

Cefcapene pivoxil hydrochloride monohydrate Basic Attributes

Molecular Weight：

622.11

Exact Mass：

621.132996

EC Number：

1592732-453-0

UNII：

V16A6AYI9H

DSSTox ID：

DTXSID7048582

NCI Thesaurus Code：

C98219

Color/Form：

White to Off-White

HScode：

2941.90.5000

Characteristics

PSA：

248

Density：

1.47 g/cm3

Melting Point：

158-164°C

Boiling Point：

888.4°C at 760 mmHg

Flash Point：

491.1ºC

Storage Conditions：

0-10°C

Critical Temperature & Pressure：

Keep in dark place,Inert atmosphere,2-8°C

Safety Information

wgk germany：

WGK 3

RTECS Number：

XI0325000

Drug Information

MeSH Entry Terms：

cefcapene pivoxil hydrochloride

Cefcapene pivoxil hydrochloride monohydrate Use and Manufacturing

Antibacterial. Orally absorbed cephalosporin; ester prodrug of the active free acid metabolite, cefcapene

Computed Properties

Molecular Weight:622.1
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:13
Rotatable Bond Count:13
Exact Mass:621.1329977
Monoisotopic Mass:621.1329977
Topological Polar Surface Area:248
Heavy Atom Count:40
Complexity:1060
Defined Atom Stereocenter Count:2
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Not yet clear

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Cefcapene Pivoxil Hydrochloride Tablets
Indication	If used with other drugs, drug interactions may occur. Please consult your doctor or pharmacist for details.
Specifications	0.1g (calculated as C17H19N5O6S2)
Manufacturer	Jiangsu Hansoh Pharmaceutical Group Co., Ltd.

Cefcapene Pivoxil Hydrochloride
Indication	Antacids and H2 receptor antagonists have no effect on the pharmacokinetics of this product. So far, there have been no reports of this product affecting laboratory test values and/or methods, and no damage to renal function has been observed in patients receiving concomitant diuretic therapy when using this product.
Specifications	Tablets: 75 mg; 100 mg. Granules: 100 mg.

Cefcapene Pivoxil Hydrochloride
Manufacturer	Jiangsu Hansoh Pharmaceutical Group Co., Ltd.

See More Related Drugs

Registered Holders

Guangzhou Tosun Pharmaceutical Ltd

China
Active
China UNION Chempharma (SUZHOU) Co., Ltd.

China
Active
Tianjin Xingshi Pharmaceutical Co., Ltd.

China
Active

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CAS No.: 147816-24-8

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CAS No.: 147816-24-8

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Guide of Cefcapene pivoxil hydrochloride monohydrate

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
Latest News
Learn More Other Chemicals

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