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Home > Encyclopedia > Desmethylicaritin

Desmethylicaritin

Desmethylicaritin structure

Desmethylicaritin 

structure
  • CAS No:

    28610-31-3

  • Formula:

    C20H18O6

  • Chemical Name:

    Desmethylicaritin

  • Synonyms:

    4H-1-Benzopyran-4-one,3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-;Flavone,3,4′,5,7-tetrahydroxy-8-(3-methyl-2-butenyl)-;4H-1-Benzopyran-4-one,3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-;3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one;Noranhydroicaritin;De-O-methylanhydroicaritin;8-Prenylkaempferol;Desmethylicaritin;4′-Desmethylicaritin;8-C-Prenylkaempferol;Desmethylanhydroicaritin;3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)chromen-4-one

  • Categories:

    Natural Products  >  Flavonoids

Description

Yellow Solid

Desmethylicaritin Basic Attributes

354.358

354.35

0V5XK67Y0S

DTXSID70415743

Characteristics

107

4.4

1.444±0.06 g/cm3(Predicted)

226 °C

Refrigerator

Drug Information

8-prenylkaempferol

Desmethylicaritin Use and Manufacturing

Uses

A metabolite of Icariin. Icaritin and Desmethylicaritin, two metabolites of Icariin, dramatically inhibit the growth of most malignant cells. They also have significant antiangiogenesis properties, inhibiting or eliminating entirely the development of new malignant cells.

Polyketides [PK] -> Flavonoids [PK12] -> Flavones and Flavonols [PK1211]

Computed Properties

Molecular Weight:354.4
XLogP3:4.4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:354.11033829
Monoisotopic Mass:354.11033829
Topological Polar Surface Area:107
Heavy Atom Count:26
Complexity:597
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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