Proteinase K
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Proteinase K
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CAS No:
39450-01-6
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Chemical Name:
Proteinase K
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Synonyms:
Proteinase K;Proteinase,Tritirachium album serine;Tritirachium album proteinase K;Endopeptidase K;E.C. 3.4.21.64;Protease K;Prok;Proteinase,serine (Tritirachium album)
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CAS No:
Description
Powder beige
An enzyme that catalyzes the hydrolysis of keratin, and of other proteins with subtilisin-like specificity. It hydrolyses peptide amides. Endopeptidase K is from the mold Tritirachium album Limber. (Enzyme Nomenclature, 1992) EC 3.4.21.64.
Characteristics
198
2.50
white powder
1.3±0.1 g/cm3
1.648
H2O: 10 mg/mL, slightly hazy, brown-yellow
2-8°C
Safety Information
NONH for all modes of transport
1
36/37/38-42
23-24-26-36/37-22-45
Xn
P261-P280-P284-P304 + P340 + P312-P337 + P313-P342 + P311
H315-H319-H334-H335
|Danger|H315 (99.46%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P272, P280, P285, P302+P352, P304+P340, P304+P341, P305+P351+P338, P312, P321, P332+P313, P333+P313, P337+P313, P342+P311, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 185 companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Proteinase K Use and Manufacturing
Inactivation of nuclease protein during separation of DNA and RNA. Remove endotoxin constraints on cationic proteins, such as lysozyme and ribonuclease. The research report shows that the enzymes used to isolate the liver, yeast, and mung bean mitochondria to measure the cell membrane are used for antibody labeling, and the antigen binding sites are exposed in paraffin-embedded tissue sections. Digesting proteins from brain tissue samples for the study of prion infectious spongiform encephalopathy (TSE)
Computed Properties
Molecular Weight:626.5
XLogP3:2.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:11
Exact Mass:626.13016130
Monoisotopic Mass:626.13016130
Topological Polar Surface Area:198
Heavy Atom Count:44
Complexity:1180
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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