Esculentoside A
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Esculentoside A
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CAS No:
65497-07-6
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Formula:
C42H66O16
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Chemical Name:
Esculentoside A
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Synonyms:
Olean-12-ene-28,29-dioic acid,3-[(4-O-β-D-glucopyranosyl-β-D-xylopyranosyl)oxy]-2,23-dihydroxy-,29-methyl ester,(2β,3β,4α,20β)-;Phytolaccoside E;Phytolaccasaponin E;Esculentoside A;Phytolaccagenin,3-(4-O-β-D-glucopyranosyl-β-D-xylopyranoside);3-O-(4-O-β-D-Glucopyranosyl-β-D-xylopyranosyl)phytolaccagenin;66702-31-6
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CAS No:
Description
Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta[1].Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models[2], has selective inhibitory activity towards cyclooxygenase-2 (COX-2)[1].Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways[3].
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