Laminaran
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Laminaran
structure -
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CAS No:
9008-22-4
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Chemical Name:
Laminaran
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Synonyms:
Laminaran;Laminarin;β-D-Glucan,(1→3)-;Goemar H 11;Iodus 40;Frontiere
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CAS No:
Description
Laminaran is a neutral water-soluble β-1-3-glucan and a typical ligand for Dectin-1 isolated from the brown alga D. dichotoma, has potent immunomodulating, radioprotective, and anticancer activities[1]. Laminaran is made up of β (1→3)-glucan with β (1→6)-branches and can be catalyzed by enzymes such as laminarinase (EC 3.2.1.6) that breaks the β (1→3) bonds[2]. Laminaran is a promising immune stimulatory molecule for use in cancer immunotherapy[3].
Characteristics
268.68000
-6.08
White to Off-white powder
1.8±0.1 g/cm3
902.8±65.0 °C at 760 mmHg
499.8±34.3 °C
1.673
soluble in dimethyl sulfoxide (slightly, heated). Slightly soluble in water.H2O: 20 mg/mL, clear, faintly yellow
2-8°C
Drug Information
Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS. (See all compounds classified as Hypolipidemic Agents.)|Agents that prevent BLOOD CLOTTING. (See all compounds classified as Anticoagulants.)
laminaran
Laminaran Use and Manufacturing
Laminaran: ACTIVE|XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).
Agrochemicals -> Elicitors
Computed Properties
Molecular Weight:504.4
XLogP3:-5.8
Hydrogen Bond Donor Count:11
Hydrogen Bond Acceptor Count:16
Rotatable Bond Count:7
Exact Mass:504.16903493
Monoisotopic Mass:504.16903493
Topological Polar Surface Area:269
Heavy Atom Count:34
Complexity:641
Defined Atom Stereocenter Count:12
Undefined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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