Periplocin
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Periplocin
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CAS No:
13137-64-9
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Formula:
C36H56O13
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Chemical Name:
Periplocin
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Synonyms:
Card-20(22)-enolide,3-[(2,6-dideoxy-4-O-β-D-glucopyranosyl-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-,(3β,5β)-;Periplocin;(3β,5β)-3-[(2,6-Dideoxy-4-O-β-D-glucopyranosyl-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxycard-20(22)-enolide;Periplocoside;Periplogenin 3-O-[β-D-glucopyranosyl-(1→4)-β-D-cymaropyranoside];20728-06-7;30899-79-7;802562-53-4
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CAS No:
Description
Periplocin is a cardiotonic steroid isolated from Periploca forrestii. Periplocin promotes tumor cell apoptosis and inhibits tumor growth. Periplocin has the potential to facilitate wound healing through the activation of Src/ERK and PI3K/Akt pathways mediated by Na/K-ATPase[1][2].
Characteristics
194
-0.4
1.1241 (rough estimate)
224 °C (decomp) @ Solvent: Acetone
610.7°C (rough estimate)
272.8±27.8 °C
1.7500 (estimate)
7.937g/L(cold water)
0mmHg at 25°C
LD in rabbits, rats (mg/kg): 10, 480 s.c. (MacKeith)
D20 +32°
Safety Information
P260, P264, P270, P271, P284, P301+P310, P304+P340, P310, P314, P320, P321, P330, P403+P233, P405, P501
H300
Computed Properties
Molecular Weight:696.8
XLogP3:-0.4
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:13
Rotatable Bond Count:7
Exact Mass:696.37209184
Monoisotopic Mass:696.37209184
Topological Polar Surface Area:194
Heavy Atom Count:49
Complexity:1280
Defined Atom Stereocenter Count:17
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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