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Periplocin

Periplocin structure

Periplocin 

structure
  • CAS No:

    13137-64-9

  • Formula:

    C36H56O13

  • Chemical Name:

    Periplocin

  • Synonyms:

    Card-20(22)-enolide,3-[(2,6-dideoxy-4-O-β-D-glucopyranosyl-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-,(3β,5β)-;Periplocin;(3β,5β)-3-[(2,6-Dideoxy-4-O-β-D-glucopyranosyl-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxycard-20(22)-enolide;Periplocoside;Periplogenin 3-O-[β-D-glucopyranosyl-(1→4)-β-D-cymaropyranoside];20728-06-7;30899-79-7;802562-53-4

  • Categories:

    Biochemical Engineering  >  Plant Extracts

Description

Periplocin is a cardiotonic steroid isolated from Periploca forrestii. Periplocin promotes tumor cell apoptosis and inhibits tumor growth. Periplocin has the potential to facilitate wound healing through the activation of Src/ERK and PI3K/Akt pathways mediated by Na/K-ATPase[1][2].

Periplocin Basic Attributes

696.825

696.82

199X940O3K

Characteristics

194

-0.4

1.1241 (rough estimate)

224 °C (decomp) @ Solvent: Acetone

610.7°C (rough estimate)

272.8±27.8 °C

1.7500 (estimate)

7.937g/L(cold water)

0mmHg at 25°C

LD in rabbits, rats (mg/kg): 10, 480 s.c. (MacKeith)

D20 +32°

Safety Information

P260, P264, P270, P271, P284, P301+P310, P304+P340, P310, P314, P320, P321, P330, P403+P233, P405, P501

H300

Drug Information

periplocin

Computed Properties

Molecular Weight:696.8
XLogP3:-0.4
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:13
Rotatable Bond Count:7
Exact Mass:696.37209184
Monoisotopic Mass:696.37209184
Topological Polar Surface Area:194
Heavy Atom Count:49
Complexity:1280
Defined Atom Stereocenter Count:17
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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