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AZD-2858

AZD-2858 structure

CAS No:
486424-20-8
Formula:
C21H23N7O3S
Chemical Name:
AZD-2858
Synonyms:
AZD 2858;AZD2858;AZD-2858;3-Amino-6-[4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-N-3-pyridinyl-pyrazinecarboxamide;2-Pyrazinecarboxamide, 3-amino-6-[4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-N-3-pyridinyl-;3-Amino-6-[4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-N-3-pyridinyl-pyrazinecarboxamide AZD2858;3-Amino-6-(4-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-N-(pyridin-3-yl)pyrazine-2-carboxamide
Categories:
Biochemical Engineering > Inhibitors

Description

AZD2858 is a potent, orally active GSK-3 inhibitor, with IC50s of 0.9 and 5 nM for GSK-3α and GSK-3β, respectively, used in the research of fracture healing.

AZD-2858 Basic Attributes

Molecular Weight：

453.51742

Exact Mass：

453.158295

Characteristics

PSA：

143

XLogP3：

0.7

Density：

1.4±0.1 g/cm3

Refractive Index：

1.663

Safety Information

Precautionary statement(s)：

P201, P202, P260, P264, P270, P281, P301+P310, P308+P313, P314, P321, P330, P405, P501

Hazard Statements：

H301

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